OVERVIEW: Synonyms Monoclonal CD4 antibody, Anti-CD4 antibody, Ly-4 antibody, Lymphocyte antigen CD4 antibody, included antibody, Leu3 antibody, CD4+ Lymphocyte deficiency, T-cell surface antigen T4/Leu-3 antibody, CD4 antigen (p55) antibody, T-cell surface glycoprotein CD4 antibody, , T cell surface antigen T4/Leu 3 antibody, L3T4 antibody, CD-4, W3/25 antigen antibody, CD 4 antibody, included antibody, MGC165891 antibody, T Cell Antigen T4 antibody, T cell differentiation antigen L3T4 antibody, T Cell Surface Glycoprotein CD4 antibody, CD4, W3/25 antibody, p55 antibody, T cell surface antigen T4/Leu3 antibody, CD4_HUMAN antibody, CD 4, CD-4 antibody, L3T4 antibody, CD4mut antibody, T cell OKT4 deficiency, T cell antigen T4/LEU3 antibody Cross Reactivity To be determined by end-user Applications ELISA, WB Immunogen CD4 antibody was raised in mouse using full length recombinant CD4 (T cell) produced in baculovirus expression system as the immunogen. SPECIFICATIONS: Host Mouse Clone 45 Isotype IgG1 Purity > 95% pure Form & Buffer Supplied lyophilized from PBS buffer, with no preservatives added, reconstitute in sterile distilled water. STORAGE & SAFETY: Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -70 deg C for long term storage. Avoid repeated freeze/thaw cycles. Usage Assay Information: Usage Recommendations ELISA: 1:1,000, WB: 1:5,000 GENERAL INFORMATION: Biological Significance CD4 (cluster of differentiation 4) is a glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells. It was discovered in the late 1970s and was originally known as leu-3 and T4 (after the OKT4 monoclonal antibody that reacted with it) before being named CD4 in 1984. In humans, the CD4 protein is encoded by the CD4 gene.