OVERVIEW: Synonyms Monoclonal Nicotinic Acetycholine Receptor alpha 4 antibody, Anti-Nicotinic Acetycholine Receptor alpha 4 antibody, Nicotinic Acetycholine Receptor alpha-4 antibody, Nicotinic Acetycholine Receptor alpha 4, Nicotinic Acetycholine Receptor alpha-4, Nicotinic Acetycholine Receptor alpha 4, Nicotinic Acetycholine Receptor alpha 4 antibody Specificity Human Cross Reactivity To be determined by end-user Applications IHC Immunogen Nicotinic Acetycholine Receptor Alpha 4 antibody was raised in Mouse using Recombinant protein corresponding to the nicotinic acetylcholine receptor alpha-4 molecule as the immunogen. SPECIFICATIONS: Host Mouse Clone 8A4 Form & Buffer Lyophilized tissue culture supernatant containing 15mM NaN3. STORAGE & SAFETY: Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling. Usage Assay Information: Usage Recommendations IHC: 1:100-1:200 GENERAL INFORMATION: Biological Significance The Nicotinic Acetylcholine Receptors are members of a superfamily of ligand gated ion channels that mediate fast signal transmission at synapses. These receptors are thought to be hetero pentamers composed of homologous subunits. The proposed structure for each subunit is a conserved N terminal extracellular domain followed by three conserved transmembrane domains, a variable cytoplasmic loop, a fourth conserved transmembrane domain, and a short C terminal extracellular region.