OVERVIEW: Synonyms Monoclonal Rat anti Mouse kappa light chain antibody, Anti-Rat anti Mouse kappa light chain antibody, Mouse kappa light chain antibody, Anti Rat anti Mouse kappa light chain antibody, Rat anti Mouse kappa light chain antibody, Mouse kappa light chain antibody Specificity Murine Cross Reactivity To be determined by end-user Applications ELISA, IHC Immunogen Rat anti-mouse kappa light chain antibody was raised in rat using murine IgG1 kappa as the immunogen. SPECIFICATIONS: Host Rat Clone LO-MK-1 Isotype IgG2a kappa Form & Buffer PBS with 0.1% NaN3. Concentration 1.0 mg/ml STORAGE & SAFETY: Storage Aliquot and store at -20 deg C. Avoid repeated Freeze/Thaw cycles Biohazard Information This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling. Usage Assay Information: Usage Recommendations Optimal conditions to be determined by end user GENERAL INFORMATION: Biological Significance There are two types of light chain in mammals, the kappa chain; encoded by the immunoglobulin kappa locus on chromosome 2, and the lambda chain; encoded by the immunoglobulin lambda locus on chromosome 22. Antibodies are produced by B lymphocytes, each expressing only one class of light chain. Once set, light chain class remains fixed for the life of the B lymphocyte.