OVERVIEW: Synonyms Monoclonal HIV1 tat antibody, Anti-HIV1 tat antibody, Human tat interactive antibody mRNA complete cds antibody, HTATIP1 antibody, HIV tat 1 antibody, HIV 1 Tat interacting antibody antibody, Transactivating regulatory antibody antibody , HIV1 tat, HIV tat-1, antibody Tat antibody, HIV tat-1 antibody, HIV-1 tat antibody, TIP antibody, Tat interactive antibody (60kD) antibody, PLIP antibody, 2interacting antibody antibody 60 kDa Tat interactive antibody antibody cPLA antibody cPLA2 antibody EC 2.3.1.48 antibody ESA1 antibody Histone acetyltransferase HTATIP antibody HIV 1 Tat interacting antibody 60kDa antibody, HIV 1 tat antibody, HIV tat 1, TIP60 antibody Specificity HIV-1 tat Cross Reactivity To be determined by end-user Applications ELISA, WB Immunogen HIV1 tat antibody was raised in mouse using full length recombinant tat (HIV-1) as the immunogen. SPECIFICATIONS: Host Mouse Clone tMAb-B Isotype IgG Purity > 95% pure Form & Buffer Supplied lyophilized from PBS buffer, with no preservatives added, reconstitute in sterile distilled water. STORAGE & SAFETY: Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -70 deg C for long term storage. Avoid repeated freeze/thaw cycles. Usage Assay Information: Usage Recommendations ELISA: 1:500-1:1,000, WB: 1:500-1:1,000 GENERAL INFORMATION: Biological Significance HIV1 tat protein is a pleiotropic factor that induces a broad variety of biological effects in numerous cell types. At the HIV promoter, tat is a powerful transactivator of gene expression which acts by inducing chromatin remodeling and by recruiting elongation-competent transcriptional complexes on to the viral LTR.