OVERVIEW: Synonyms Monoclonal HTLV1 tax antibody, Anti-HTLV1 tax antibody, HTLV 1, HTLV 1 tax antibody, HTLV-1 antibody, HTLV1, HTLV-1, HTLV-1 tax antibody, HTLV 1 p40 antibody, Human T Lymphotrophic Virus Type 1 tax antibody, p40 antibody, HTLV 1 antibody, tax antibody Specificity HTLV-1 tax Cross Reactivity To be determined by end-user Applications WB Immunogen HTLV-1 tax antibody was raised in mouse using purified, full length tax (HTLV-I) as the immunogen. SPECIFICATIONS: Host Mouse Clone 810001 Isotype IgG1 Purity > 90% pure Form & Buffer Supplied lyophilized from PBS buffer, with no preservatives added, reconstitute in sterile distilled water. STORAGE & SAFETY: Storage Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -70 deg C for long term storage. Avoid repeated freeze/thaw cycles. Usage Assay Information: Usage Recommendations WB: 1:500-1:1,000 GENERAL INFORMATION: Biological Significance The Human T-lymphotropic virus Type I (HTLV-1) is a human RNA retrovirus that causes T-cell leukemia and T-cell lymphoma in adults and may also be involved in certain demyelinating diseases, including tropical spastic paraparesis. The HTLV-1 genome is diploid, composed of two copies of a single-stranded RNA virus whose genome is copied into a double-stranded DNA form that integrates into the host cell genome, at which point the virus is referred to as a provirus.