首页 > Exalpha > Exalpha/Mouse anti Human p16 – ink4a/100 µg/C170M

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Exalpha/Mouse anti Human p16 – ink4a/100 µg/C170M

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C170M

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Mouse anti Human p16 – ink4aCatalogue number: C170MCloneDCS50.1 IsotypeIgG1 Product Type Monoclonal AntibodyUnits100 µg HostMouse Species reactivity HumanApplication ImmunohistochemistryImmunoprecipitationWestern BlotWestern Blotting BackgroundThe immunogen for the anti-human p16 was a recombinantfull lengthp16protein recognizing a 16kDa protein. The p16ink4a tumor suppressor protein shows no cross reactivity with the closely related inhibitors such as p15ink4b and p18ink4c.p16ink4a is a specific inhibitor of cdk4/cdk6, and is atumor suppressorinvolvedin thepathogenesisofanumberofmalignanciesincluding melanoma and lung carcinoma.Synonyms: hp16; p16 ink4a; Cyclin dependent kinase inhibitor 2A, isoforms 1/2/3; Cyclin-dependent kinase 4 inhibitor A; CDK4I Source Immunogen: A recombinant full length p16 protein recognizing a 16kDa protein Product Product Form: Unconjugated Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide Purification Method: Protein A/G ChromatographyConcentration: See vial for concentration ApplicationsApplications: Western Blot, Immunoflurescence, Immunoprecipitation (co-precipitates cdk4/cdk6)Functional Analysis: Western Blotting StorageProduct should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles Product Stability: Products are stable for one year from purchase when stored properly Shipping Conditions: Ship at ambient temperature, freeze upon arrival CautionThis product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but Exalpha Biologicals accepts no liability for any inaccuracies or omissions in this information. References 1) J. Lukas et.al (1995) Nature., 375,503-506 2) L. Aagaard et.al. (1995), Intl. J. of Cancer 61(1) 115-120 Protein Reference(s)Database Name: UniProt Accession number: P42771 (Human) Species Accession: Human Safety Datasheet(s) for this product:EA_Sodium Azide/wp-content/uploads/SDS/Antibody SDS with Sodium AzideV2.pdf

xalpha有限公司于2000年在马萨诸塞州雪莉（美国）成立。该公司主要通过开发和生产一流的抗体来支持生命科学领域的研究人员和科学家。其领域涉及信号通路、凋亡、增殖、炎症、免疫学、传染病学和细胞间结构研究等方面。Exalpha主要产品线包括Proliferation&apoptosis, Enzymes&Proteins, Clinical IHC Markers , GPCRs等多个产品线，可提供给全球的科研实验室，制药企业，生物技术和诊断公司，医院等，目前旗下的代理公司遍布全球。