产品说明
SpecificationsSPECIES:HumanSOURCESPECIES:E.coliSEQUENCE:Arg71-Glu254FUSIONTAG:C-6HistagTESTEDAPPLICATIONS:APPLICATIONS:ThisrecombinantproteincanbeusedforBIOLOGicalassays.Forresearchuseonly.PropertiesPURITY:Greaterthan95%asdeterminedbyreducingSDS-PAGE.Endotoxinlevellessthan0.1ng/ug(1IEU/ug)asdeterminedbyLALtest.PREDICTEDMOLECULARWEIGHT:20.6kDPHYSICALSTATE:LyophilizedBUFFER:Lyophilizedfroma0.2umfilteredsolutionof20mMPB,150mMNaCl,pH7.4.Itisnotrecommendedtoreconstitutetoaconcentrationlessthan100ug/ml.DissolvethelyophilizedproteininddH2O.STORAGECONDITIONS:Lyophilizedproteinshouldbestoredat-20˚C,thoughstableatroomtemperaturefor3weeks.Reconstitutedproteinsolutioncanbestoredat4-7˚Cfor2-7days.Aliquotsofreconstitutedsamplesarestableat-20˚Cfor3months.AdditionalInfoALTERNATENAMES:Tumornecrosisfactorligandsuperfamilymember9,4-1BBligand,4-1BBL,TNFSF9.,TNFSF9,CD137LACCESSIONNO.:P41273PROTEINGINO.:578833707BackgroundTumornecrosisfactorligandsuperfamilymember9,alsoknownas4-1BBL,isamemberofthethetumornecrosisfactorfamily.Itisa254aminoacidscytokinethatisexpressedinbrain,placenta,lung,skeletalmuscleandkidney.TNFSF9hasbeenshowntoreactivateanergicTlymphocytesinadditiontopromotingTlymphocyteproliferation.ThiscytokinehasalsobeenshowntoberequiredfortheoptimalCD8responsesinCD8Tcells,andisthoughttobeinvolvedinTcell-tumorcellinteraction.
ProSci
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