产品说明
SpecificationsSPECIESREACTIVITY:HumanTESTEDAPPLICATIONS:WBAPPLICATIONS:ForWBstartingdilutionis:1:1000ForFACSstartingdilutionis:1:10~50USERNOTE:Optimaldilutionsforeachapplicationtobedeterminedbytheresearcher.PREDICTEDMOLECULARWEIGHT:51kDaIMMUNOGEN:This5HT3EantibodyisgeneratedfromrabbitsimmunizedwithaKLHconjugatedsyntheticpeptidebetween126-154aminoacidsfromtheCentralregionofhuman5HT3E.HOSTSPECIES:RabbitPropertiesPURIFICATION:ThisantibodyispurifiedthroughaproteinAcolumn,followedbypeptideaffinitypurification.PHYSICALSTATE:LiquidBUFFER:SuppliedinPBSwith0.09%(W/V)sodiumazide.CONCENTRATION:0.5mg/mlSTORAGECONDITIONS:Storeat4˚Cforthreemonthsand-20˚C,stableforuptooneyear.Aswithallantibodiescareshouldbetakentoavoidrepeatedfreezethawcycles.Antibodiesshouldnotbeexposedtoprolongedhightemperatures.CLONALITY:PolyclonalISOTYPE:RabbitIgCONJUGATE:UnconjugatedAdditionalInfoALTERNATENAMES:5-hydroxytryptaminereceptor3E,5-HT3-E,5-HT3E,SEROtoninreceptor3E,HTR3EACCESSIONNO.:A5X5Y0OFFICIALSYMBOL:HTR3EGENEID:285242BackgroundBACKGROUND:Theproductofthisgenebelongstotheligand-gatedionchannelreceptorsuperfamily.HTR3EencodesasubunitEofthetype3receptorfor5-hydroxytryptamine(serotonin),abiogenichormonethatfunctionsasaneurotransmitter,ahormone,andamitogen.Thisreceptorcausesfast,depolarizingresponsesinneuronsafteractivation.GenesencodingsubunitsC,DandEformaclusteronchromosome3.Analternativesplicevarianthasbeendescribedbutitsfulllengthsequencehasnotbeendetermined.REFERENCES:1)Walstab,J.,etal.J.Biol.Chem.285(35):26956-26965(2010)2)Hammer,C.,etal.Pharmacogenomics11(7):943-950(2010)3)Lennertz,L.,etal.EurNeuropsychopharmacol20(6):414-420(2010)4)Goecke,T.W.,etal.ActaObstetGynecolScand89(1):7-14(2010)
ProSci
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