首页 > JPT > JPT/SpikeTides™ PTM-Peptide 26-00 - Glyco-Unmodified - quantified/SPT-PTM-TQL-P26-00-Glyco-Unmodified

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JPT/SpikeTides™ PTM-Peptide 26-00 - Glyco-Unmodified - quantified/SPT-PTM-TQL-P26-00-Glyco-Unmodified

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SPT-PTM-TQL-P26-00-Glyco-Unmodified

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SpikeTides™PTM-Peptide26-00-Glyco-Unmodified-quantifiedProductCode:SPT-PTM-TQL-P26-00-Glyco-UnmodifiedAbsolutelyquantifiedproteotypicpeptidefordirectusageasreferencematerialinmass-spectrometrybasedproteomics:H-PEENLILDAQATS-R*-Qtag.Amount:1peptide(5000pmol/peptide)DeliveryFormat:PolypropylenevialApplication(s):MRMassays,Massspectrometry,Proteomics,SRMassays,PTMproteomicsIndication(s)/Topic(s):ControlDeliveryTime:2-3weeksSpikeTides™QuantifiedPTMReferenceKits&PeptidesDespiterecentimprovements,PTMproteomicsisstillchallenging.Typicalproblemsarelowendogenousabundance,lowionizationintensity,changedfragmentation,limitedstABIlityduringproteomicsworkflows,and/orcomplexfragmentationspectrainterpretation,especiallyregardingcorrectPTMsitelocalization.OurdefinedandcarefullyselectedsyntheticPTMreferencepeptidessupportPTMproteomicsandhelptoovercomethesechallengesandareapplicablefordirectusageasreferencematerialinmass-spectrometrybasedproteomics.AvailablePTMsaspeptidekitsorindividualpeptides:Phospho(serine,threonine,tyrosine),Arg(Me,Me2a,Me2s),Lys(Ac,Me,Me2,Me3,Cro,Suc,Mal,Biotin,Glu,For,Prop,But,Hib,GG),Sulfotyrosine,Glyco-Asn(betaDGlcNAc),Glyco-Thr(alphaDGalNAc),Glyco-Ser(alphaDGalNAc).Thepeptidesarepartofacollectionof142peptidesthatcompriseswild-typepeptidesaswellas23differentpost-translationalmodifications(PTMs).QuantificationwithQtag:OurpeptidequantitationtechniqueshowsseveraladvantagesovertrADItionalquantitationmethods.WeuseasmallchemicalQtagattachedtothepeptideforprecisepeptidequantitation.TheQtagisreleasedformthepeptideduringtrypsinationofthesample.FurtherinformationBenefitsofSpikeTides™QuantifiedPTMReferenceKits&Peptides-LargerangeofPTMreferencepeptides-SelectedforhighrecoveryinLC-MS-Stable-isotopelabeled(SIL)-Purifiedandabsolutelyquantified

JPT的关键技术平台基于该公司强大而长期的技术，化学和生物学背景。JPT已经开发了几种独特的方法，可解决细胞疗法和疫苗开发过程的所有阶段，包括生物标记物发现，新表位优先，免疫监测和疫苗功效测试。
此外，这四个技术平台为靶向蛋白质组学和分子诊断奠定了基础。JPT的技术在需要进行肽筛查的领域中得到了广泛的应用。典型示例包括：筛选蛋白肽，酶活性（蛋白酶，激酶，磷酸酶，甲基转移酶）或肽前导结构的系统优化。