首页 > Hycult Biotech > Hycult Biotech/SP-D, Rat, mAb VIF9, immuno assay antibody/HM3023-IA/0.5 mg

提醒：代购产品，无质量问题不接受退换货，下单前请仔细核对信息。下单后请及时联系客服核对商品价格，订单生效后再付款。

Hycult Biotech/SP-D, Rat, mAb VIF9, immuno assay antibody/HM3023-IA/0.5 mg

价格：

登录查看

自营商城

解放采购

正品保障

及时交付

厂家直采

一站服务

货号：

HM3023-IA

品牌：

Hycult Biotech

会员服务：

尊享会员价

贵宾专线

运费优惠

闪电退款

福利优惠

上门换新

友情提示

以上价格仅为参考，请联系客服询价。

免费咨询热线

4000-520-616

产品说明

Description:SP-D,Rat,mAbVIF9,immunoassayantibodyThemonoclonalantibodyVIF9recognizestheratsurfactantproteinD(SP-D).SP-Dbelongstothecollectinfamiliy.Theseproteinsareoligomericproteinscomposedofcarbohydrate-recognitiondomains(CRD)attachedtocollagenousregions.TheyarestructurallysimilartotheficolinsalthoughtheymakeuseofdifferentCRDstructures:C-typelectindomainforthecollectins.Theanti-microbialeffectormechanismsofSP-Daredirectopsonization,neutralization,andagglutination.Thuslimitingtheinfectionandconcurrentlyorchestratingthesubsequentadaptiveimmuneresponse.ThelungisthemajorsiteofsynthesisofSP-D,wherethemoleculesareproducedandsecretedontotheepithelialsurfacebyalveolartypeIIcellsandunciliatedbronchialepithelialcells.SP-Disalsofoundindifferentepithelialcellsofthegastrointeststinaltractandinepithelialcellsofexocrineglands.SP-Dsynthesisandsecretionincreasesignificantlyafterinflammatorystress.IncreasedamountsofSP-Dinlavageandtissue,particularlyintypeIIpneumocytes,inClaracellsandinhyperplasticgobletcellsarefoundininflamedlungs.ThelocalizationofSP-Dinendocyticvesiclesandinlysosomalgranulesofalveolarmacrophagessuggeststhatareceptor-mediateduptakeoccurs.SP-Dbindstoapoptoticneutrophilsandenhancestheirclearancebyalveolarmacrophages.MonoclonalantibodyVIF9specificforratsurfactantproteinDshowssignificantcrossreactivitywithhumanSP-D.MonoclonalantibodyVIF9stainsparaffinsectionsofratlung.Itcannotbeusedforstainingofparaffinsectionsofhumanlung.ItcanalsobeusedasdetectionantibodyforELISAonwellscoatedwithhumanSP-D.Specifications:CatalognumberHM3023-IAProducttypeMonoclonalantibodiesQuantity0.5mgFormulation0.5mgof0.2μmfilteredproteinGpurifiedantibodysolutioninPBS(exactconcentrationisindicatedonthelabel).ApplicationImmunoassays,Paraffinsections,WesternblotApplicationNotesIA:HM3023canbeusedasacaptureanddetectionantibody.W:Anon-reducedsampletreatmentandSDS-Pagewasused.Thebandsizeis~47kDa.UseDilutionstobeuseddependondetectionsystemapplied.Itisrecommendedthatuserstestthereagentanddeterminetheirownoptimaldilutions.Thetypicalstartingworkingdilutionis1:50.ImmunogenPurifiedRatSP-DIsotypeMouseIgG1SpeciesRatCrossreactivityHuman-Yes,Mouse-YesAliasPulmonarysurfactant-associatedproteinD,PSP-D,CP-4,LungsurfactantproteinDGenename:Sftpd,Sftp4References1.Kasper,Metal;MonoclonalantibodiestosurfactantproteinD:evaluationofimmunoreactivityinnormalratlungandinarADIation-inducedfibrosismodel.ExpLungRes1995,21:5772.Jain,Detal;SurfactantProteinDProtectsagainstAcuteHyperoxicLungInjury.AmJRespCritCare2008,17:806StorageandstABIlityProductshouldbestoredat4 °C.Underrecommendedstorageconditions,productisstableforoneyear.PrecautionsForresearchuseonly.Notforuseinoronhumansoranimalsorfordiagnostics.Itistheresponsibilityoftheusertocomplywithalllocal/stateandFederalrulesintheuseofthisproduct.HycultBiotechisnotresponsIBLeforanypatentinfringementsthatmightresultwiththeuseoforderivationofthisproduct.DiseasePulmonology

荷兰HyCult Biotechnology(HBT)位于荷兰乌登，从1994开始制造检测抗体和蛋白质，主要侧重与病理学诊断有关的全套产品研发，既有纯化的重组蛋白和多肽，也有单抗和多抗，是世界一流的先天免疫领域的研究试剂制造商。