首页 > ACROBiosystems > ACROBiosystems/Human BMPR-IA / ALK-3 Protein, His Tag/1mg (500ug × 2)/AL3

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ACROBiosystems/Human BMPR-IA / ALK-3 Protein, His Tag/1mg (500ug × 2)/AL3

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AL3

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SynonymBMPR-1A,ALK-3,10q23del,ACVRLK3,CD292,SKR5SourceHuman BMPR-IA, His Tag (AL3-H5228) is expressed from human 293 cells (HEK293). It contains AA Gln 24 - Arg 152 (Accession # P36894-1).Predicted N-terminus: Gln 24Request for sequenceMolecular CharacterizationThis protein carries a polyhistidine tag at the C-terminus.The protein has a calculated MW of 15.0 kDa. The protein migrates as 23-34 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.EndotoxinLess than 1.0 EU per μg by the LAL method.Purity>95% as determined by SDS-PAGE.FormulationLyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.Contact us for customized product form or formulation.ReconstitutionPlease see Certificate of Analysis for specific instructions.For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.StorageFor long term storage, the product should be stored at lyophilized state at -20°C or lower.Please avoid repeated freeze-thaw cycles. This product is stable after storage at: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. SDS-PAGEHuman BMPR-IA, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. BackgroundThe bone morphogenetic protein receptor, type IA is also known as BMPR1A or ALK3 is a protein which in humans is encoded by the BMPR1A gene. BMPR1A has also been designated as CD292 (cluster of differentiation 290). The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A (this protein) and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. Alk3-mediatedBMP signaling in AV endocardial/mesenchymal cells plays a central role during cushion morphogenesis. ReferencesPlease contact us via TechSupport@acrobiosystems.com if you have any question on this product.

ACROBiosystems 是一个具有全球范围影响力的生物技术领导品牌，其运营包括了位于北美、欧洲和亚洲的数家公司，主要为生命科学研究、生物制药与疫病诊断等行业提供产品、技术服务和临床应用等解决方案，同时致力于在蛋白组学、药物发现和细胞治疗等领域推广面向工业化和临床转化的技术和产品。ACROBiosystems 的业务遍及全球50多个国家和地区，并通过在北美、亚洲、欧洲等世界范围的不同时区设立分支机构以服务于当地客户与经销商。