DescriptionPublicationsQA_1Q&Abody { line-height:115%; font-family:Calibri; font-size:11pt }p { margin:0pt 0pt 10pt }table { margin-top:0pt; margin-bottom:10pt }.BalloonText { margin-bottom:0pt; line-height:normal; font-family:Tahoma; font-size:8pt }span.BalloonTextChar { font-family:Tahoma; font-size:8pt }span.Hyperlink { text-decoration:underline; color:#0000ff }.TableGrid { margin-bottom:0pt; line-height:normal }General InformationProductAdenylate Cyclase 1 AntibodyVerified ApplicationsELISA, IP, WBHostRabbitSpecies Cross ReactivityMouse, Rabbit, RatImmunogenSynthetic peptide corresponding to conserved sequence at or near C terminal end of protein that is unique to rat/mouseAdenylyl Cyclase 1 protein.Accession #GenBank: AAC29478 Physical PropertiesQuantity100 µgVolume200 µlConcentration0.55- 0.72 µg/µl in antibody stabilization bufferFormAffinity PurifiedClonalityPolyclonalStorage-20⁰C for long term storageApplication ProtocolELISA1:10,000Immunoprecipitation1:200Western Blot1:500. Detects a band 127-10 kDaProteinUniprot #O88444OverviewThis is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retinaMolecular FunctionATP-binding, Calmodulin-binding, Magnesium, Metal-binding, Nucleotide-bindingSubcellular LocationMembrane; Multi-pass membrane protein. CytoplasmExpressionExpressed throughout inner ear development. Brain, retina and adrenal medulla.StructureBelongs to the adenylyl cyclase class-4/guanylyl cyclase family.Contains 2 guanylate cyclase domainsAlternative Nomenclature3"5" cyclic AMP synthetase antibodyADCY1 antibodyadenyl cyclase antibodyAdenylate cyclase 1 antibodyATP pyrophosphate lyase antibodyBrain adenylate cyclase 1 antibodyCa(2+)/calmodulin activated adenylyl cyclase antibodyEC 4.6.1.1 antibodyProtein information supplied by UniProtbody { line-height:115%; font-family:Calibri; font-size:11pt }p { margin:0pt 0pt 10pt }table { margin-top:0pt; margin-bottom:10pt }span.Hyperlink { text-decoration:underline; color:#0000ff }.TableGrid { margin-bottom:0pt; line-height:normal }Fabgennix Adenylate cyclase 1 Antibody has been used in 3 PublicationsNakamura, Akio, Makoto Miyagawa, and Yukishige Yanagawa. "Modulation of 11β-hydroxysteroid dehydrogenase 1 by β2-adrenoceptor in the ischaemia-reperfused rat kidney." Nephrology Dialysis Transplantation 27.9 (2012): 3456-3464. PMID22187316Western Blot; RatNakamura, Akio, Ryo Niimi, and Yukishige Yanagawa. "Protection from sepsis-induced acute renal failure by adenoviral-mediated gene transfer of β2-adrenoceptor†." Nephrology Dialysis Transplantation (2009): gfp561. PMID19887504Western Blot; RatYounes, Antoine et al. “Ca2+-Stimulated Basal Adenylyl Cyclase Activity Localization in Membrane Lipid Microdomains of Cardiac Sinoatrial Nodal Pacemaker Cells.” The Journal of Biological Chemistry 283.21 (2008): 14461–14468. PMC2386925Dot Blot; RabbitPublishing research using PAC-101AP? Please let us know, we can cite the reference in this datasheet.Has the homology of AC1with other AC family members been tested or determined?Yes the cross reactivity to PAC-1-9 have been tested and found to be non-reactive. No other antibody cross react with non-homologus protein.Has the homology of AC1with other AC family members been tested or determined?Yes the cross reactivity to PAC-1-9 have been tested and found to be non-reactive. No other antibody cross react with non-homologus protein.

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货号	产品	价格
FGI-1989	StripOBuffer Western Blot Stripping Buffer	$150.00
HRP-1060	Rabbit Anti-Chicken IgG HRP	$150.00
FGI-1943	SolObuffer Cell Lysis Kit	$175.00
FGI-1963	DiluOBuffer - Antibody Dilution Buffer	$185.00
HIL2-E96.1	Human IL-2 ELISA Kit	$495.00