DescriptionPublicationsbody { line-height:115%; font-family:Calibri; font-size:11pt }p { margin:0pt 0pt 10pt }table { margin-top:0pt; margin-bottom:10pt }.BalloonText { margin-bottom:0pt; line-height:normal; font-family:Tahoma; font-size:8pt }span.BalloonTextChar { font-family:Tahoma; font-size:8pt }span.Hyperlink { text-decoration:underline; color:#0000ff }.TableGrid { margin-bottom:0pt; line-height:normal }General InformationProductADCY5 AntibodyDescriptionAffinity Purified Adenylyl cyclase type 5 mRNA Antibody Verified ApplicationsCM, ELISA, ICC, IF, IHC, IP, WBHostRabbitSpecies Cross ReactivityHuman, Rat, MouseImmunogenSynthetic peptide corresponding to unique amino acid sequence on rat Particulate Adenylyl Cyclase 5 protein.Accession #GenBank: M96159.1Physical PropertiesQuantity100 µgVolume200 µlConcentration0.5 µg/µl in antibody stabilization bufferFormAffinity PurifiedClonalityPolyclonalStorage-20⁰C for long term storageApplication ProtocolConfocal Microscopy1:200-1:1,000DB1:10,000ELISA1:10,000Immunocytochemistry1:200-1:1,000Immunofluorescence1:200-1:1,000Immunohistochemistry1:200-1:1,000Immunoprecipitation1:200Western Blot1:500ProteinUniprot #Q04400OverviewMembrane bound calcium-inhibitable adenylyl cyclase.Molecular FunctionAdenylate cyclase activity; cAMP biosynthesis; ATP-binding; Magnesium; Metal binding; Nucleotide-bindingSubcellular LocationMembrane; Multi-pass membrane protein; Cell projection; ciliumStructurePart of a complex containing AKAP5, ADCY6, PDE4C and PKD2. Interacts with RAF1.Alternative NomenclatureAC 5 antibodyAdcy5 antibodyAdenylate cyclase type V antibodyAdenylyl cyclase 5 antibodyATP pyrophosphate-lyase 5 antibodyProtein information supplied by UniProtbody { line-height:115%; font-family:Calibri; font-size:11pt }p { margin:0pt 0pt 10pt }table { margin-top:0pt; margin-bottom:10pt }span.FollowedHyperlink { text-decoration:underline; color:#800080 }span.Hyperlink { text-decoration:underline; color:#0000ff }.TableGrid { margin-bottom:0pt; line-height:normal }Fabgennix ADCY5 Antibody has been used in 9 PublicationsAkkerman, Sven et al. “PDE5 Inhibition Improves Object Memory in Standard Housed Rats but Not in Rats Housed in an Enriched Environment: Implications for Memory Models?” Ed. Patrizia Campolongo. PLoS ONE 9.11 (2014): e111692. PMC4221101Western Blot; RatKwon, Ronald Y. et al. “Primary Cilium-Dependent Mechanosensing Is Mediated by Adenylyl Cyclase 6 and Cyclic AMP in Bone Cells.”The FASEB Journal24.8 (2010): 2859–2868.PMC2909282 Confocal Microscopy, Immunofluorescence; HumanMasyuk, Anatoliy I. et al. “Cholangiocyte Primary Cilia Are Chemosensory Organelles That Detect Biliary Nucleotides via P2Y12Purinergic Receptors.”American Journal of Physiology - Gastrointestinal and Liver Physiology295.4 (2008): G725–G734.PMC2575915 Confocal Microscopy, Immunofluorescence; RatOrtiz-Capisano, M. Cecilia, et al. "Adenylyl cyclase isoform v mediates renin release from juxtaglomerular cells." Hypertension 49.3 (2007): 618-624.PMID17190869 Confocal Microscopy, Immunofluorescence, Western Blot; RatWang, Shyi-Chyi et al. “Regulation of TypeV Adenylate Cyclase by Ric8a, a Guanine Nucleotide Exchange Factor.”The Biochemical Journal406.Pt 3 (2007): 383–388.PMC2049038 Immunocytochemistry; RatIvanov, Alexander et al. “Adenylate Cyclase 5 and KCa1.1 Channel Are Required for EGFR up-Regulation of PCNA in Native Contractile Rat Basilar Artery Smooth Muscle.”The Journal of Physiology570.Pt 1 (2006): 73–84. PMC1464296 Confocal Microscopy, Immunofluorescence, Western Blot; RatGrünberger, Christian, et al. "The Calcium Paradoxon of Renin Release Calcium Suppresses Renin Exocytosis by Inhibition of Calcium-Dependent Adenylate Cyclases AC5 and AC6." Circulation research 99.11 (2006): 1197-1206.PMID17068292 Western Blot; RatMasyuk, Anatoliy I. et al. “Cholangiocyte Cilia Detect Changes in Luminal Fluid Flow and Transmit Them into Intracellular Ca2+and cAMP Signaling.”Gastroenterology131.3 (2006): 911–920.PMC1866168 Confocal Microscopy, Immunofluorescence; RatKolachala, Vasantha, et al. "Interferon-γ down-regulates adenosine 2b receptor-mediated signaling and short circuit current in the intestinal epithelia by inhibiting the expression of adenylate cyclase." Journal of Biological Chemistry 280.6 (2005): 4048-4057. PMID15550390Western Blot; HumanPublishing research using PAC-501AP? Please let us know, we can cite the reference in this datasheet.

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部分产品的详细列表：Fabgennix授权代理

货号	产品	价格
FGI-1989	StripOBuffer Western Blot Stripping Buffer	$150.00
HRP-1060	Rabbit Anti-Chicken IgG HRP	$150.00
FGI-1943	SolObuffer Cell Lysis Kit	$175.00
FGI-1963	DiluOBuffer - Antibody Dilution Buffer	$185.00
HIL2-E96.1	Human IL-2 ELISA Kit	$495.00