产品说明
Descriptionbody { line-height:115%; font-family:Calibri; font-size:11pt }p { margin:0pt 0pt 10pt }table { margin-top:0pt; margin-bottom:10pt }.BalloonText { margin-bottom:0pt; line-height:normal; font-family:Tahoma; font-size:8pt }span.BalloonTextChar { font-family:Tahoma; font-size:8pt }span.Hyperlink { text-decoration:underline; color:#0000ff }.TableGrid { margin-bottom:0pt; line-height:normal }General InformationProductAGE AntibodyDescriptionAffinity Purified Advance Glycated Endproduct Antibody Verified ApplicationsELISA, WBHostRabbitSpecies Cross ReactivityBovine, Human, Monkey, PandaImmunogenPurified glycated ribonuclease corresponding to AGE. Glycated ribonuclease (RNase) prepared by incubating RNase with glucose at 37⁰C for several months.Physical PropertiesQuantity100 µgVolume200 µlConcentration0.55 µg/µl in antibody stabilization bufferFormAffinity PurifiedClonalityPolyclonalStorage-20⁰C for long term storageApplication ProtocolDB1:10,000ELISA1:10,000Western Blot1:500ProteinOverviewMediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. Acts as a mediator of both acute and chronic vascular inflammation in conditions such as atherosclerosis and in particular as a complication of diabetes. AGE/RAGE signaling plays an important role in regulating the production/expression of TNF-alpha, oxidative stress, and endothelial dysfunction in type 2 diabetes. Interaction with S100A12 on endothelium, mononuclear phagocytes, and lymphocytes triggers cellular activation, with generation of key proinflammatory mediators. Molecular FunctionInflammatory ResponseSubcellular LocationIsoform 1 : Cell membrane; Single-pass type I membrane proteinIsoform 2 : SecretedIsoform 10 : Cell membrane 1 Publication; Single-pass type I membrane proteinExpressionEndothelial cells.StructureInteracts with S100A1 and APP (By similarity). Interacts with S100B, S100A12 and S100A14. Constitutive homodimer; disulfide-linked.Alternative NomenclatureAdvanced glycation end products antibodyAGEs antibodyProtein information supplied by UniProt
苏州蚂蚁淘Fabgennix授权代理业务。Fabgennix授权代理, Fabgennix北京代理, Fabgennix华东代理,Fabgennix华北代理,Fabgennix华中代理,Fabgennix华南代理。
Fabgennix
我们提供高质量的研究工具,专家技术支持,相关的准确数据以及快速的全球运输。我们不断在我们的库存中添加新产品,包括一级和二级抗体,试剂,试剂盒,多肽和阳性对照。我们所有的抗体都在内部开发和表征。我们为我们的Single Source Antibodies™感到自豪。
部分产品的详细列表:Fabgennix授权代理
货号 |
产品 |
价格 |
FGI-1989 |
StripOBuffer Western Blot Stripping Buffer |
$150.00 |
HRP-1060 |
Rabbit Anti-Chicken IgG HRP |
$150.00 |
FGI-1943 |
SolObuffer Cell Lysis Kit |
$175.00 |
FGI-1963 |
DiluOBuffer - Antibody Dilution Buffer |
$185.00 |
HIL2-E96.1 |
Human IL-2 ELISA Kit |
$495.00 |
新品排行榜
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FabGennix/PAX2 Antibody/PAX2-212...
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FabGennix/C1orf146 Antibody/C1OR...
3
FabGennix/CCR4 Antibody/CCR4-401...
4
FabGennix/Phospho-MERTK Antibody...
5
FabGennix/TOMM40 Antibody/TOM40-...
6
FabGennix/FPR1 Antibody/FPR1-101...
7
FabGennix/SLC9A3 Antibody/SLC9A3...
8
FabGennix/Bestrophin 3 Antibody/...
9
FabGennix/EHD1 Antibody/EHD1-101...
10
FabGennix/Ephrin Receptor A3 Ant...
文章排行榜
1
Fabgennix代理 蚂蚁淘(上海)有限公司-蚂蚁淘-蚂蚁淘生物|ebiomall
2
FabGennix/TLR10 Antibody/TLR-1001AP/
3
FabGennix/RIPK5 Antibody/RIPK5-501AP/
4
FabGennix/Phantom Antibody/PHT-121AP/
5
FabGennix/Npas4 Antibody/NPAS4-101AP/
6
FabGennix/GPCR GPR3 Antibody/GPCR3-101AP/
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FabGennix/PDE1A Antibody/PD1A-101AP/
8
FabGennix/IL12 p35 Antibody/IL12P35-101AP/
9
FabGennix/TMEPAI Antibody/TMEPA1-101AP/
10
FabGennix/FSH Antibody/FSH-101AP/