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FabGennix/Aquaporin 4 Antibody/AQP4-401AP

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AQP4-401AP

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Descriptionbody { line-height:115%; font-family:Calibri; font-size:11pt }p { margin:0pt 0pt 10pt }table { margin-top:0pt; margin-bottom:10pt }.BalloonText { margin-bottom:0pt; line-height:normal; font-family:Tahoma; font-size:8pt }span.BalloonTextChar { font-family:Tahoma; font-size:8pt }span.Hyperlink { text-decoration:underline; color:#0000ff }.TableGrid { margin-bottom:0pt; line-height:normal }General InformationProductAquaporin 4 AntibodyVerified ApplicationsELISA, ICC, IF, IHC, IP, WBHostRabbitSpecies Cross ReactivityBovine, Human, Sheep, Mouse, RatImmunogenSynthetic peptide taken within amino acid region 300-323 on rat Aquaporin 4 protein.Accession #NCBI: NP_001641Physical PropertiesQuantity100 µgVolume200 µlConcentration0.50-0.62 µg/µl in antibody stabilization bufferImmunoglobulinIgGFormAffinity PurifiedClonalityPolyclonalStorage-20⁰C for long term storageApplication ProtocolELISA1:10,000Immunocytochemistry1:100Immunofluorescence1:100Immunohistochemistry1:100Immunoprecipitation1:200Western Blot1:500ProteinUniprot #P55087OverviewForms water specific channel. Osmoreceptor which regulates water balance and mediates water flow within CNS.Molecular FunctionTransportSubcellular LocationMembrane; Multi-pass proteinExpressionAbundant in mature brain but only weakly detectable in eye, kidney, intestine, and lung.StructureAquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).Alternative NomenclatureAQP 4 antibodyAquaporin type 4 antibodyAquaporin-4 antibodyHMIWC2 antibodyMercurial insensitive water channel antibodyMGC22454 antibodyMIWC antibodyWCH 4 antibodyProtein information supplied by UniProt

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