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FabGennix/ARTS Antibody/SEPT-401AP
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Descriptionbody { line-height:115%; font-family:Calibri; font-size:11pt }p { margin:0pt 0pt 10pt }table { margin-top:0pt; margin-bottom:10pt }.BalloonText { margin-bottom:0pt; line-height:normal; font-family:Tahoma; font-size:8pt }span.BalloonTextChar { font-family:Tahoma; font-size:8pt }span.FollowedHyperlink { text-decoration:underline; color:#800080 }span.Hyperlink { text-decoration:underline; color:#0000ff }.TableGrid { margin-bottom:0pt; line-height:normal }General InformationProductARTS Antibody Affinity PurifiedDescriptionAffinity Purified Septin-4 Antibody Verified ApplicationsELISA, WBHostRabbitSpecies Cross ReactivityHuman, Mouse, RatImmunogenSynthetic peptide taken within amino acid region 400-450 on SEPT4 protein.Physical PropertiesQuantity100 µgVolume200 µlConcentration0.68-075 µg/µl in antibody stabilization bufferFormAffinity PurifiedClonalityPolyclonalStorage-20⁰C for long term storageApplication ProtocolDB1:10,000ELISA1:10,000Western Blot1:500ProteinUniprot #O43236OverviewFilament-forming cytoskeletal GTPase (By similarity). May play a role in cytokinesis (Potential). May play a role in platelet secretion. Isoform ARTS, but not the other isoforms, is required for the induction of cell death mediated by TGF-beta and by other apoptotic stimuli.Molecular FunctionGTPase activity, structural molecule activity, GTP bindingSubcellular LocationCytoplasm, cytoskeleton. (Note: In platelets, found in areas surrounding alpha-granules)ExpressionWidely expressed in adult and fetal tissues with highest expression in adult brain (at protein level), heart, liver and adrenal gland and fetal heart, kidney, liver and lung. Also expressed in colorectal cancers and malignant melanomas. Expressed in plateAlternative NomenclatureApoptosis Related Protein TGFb Signalling antibodyARTS antibodyBradeion beta antibodyBrain protein H5 antibodyCE5B3 antibodyCE5B3 beta antibodycell division control-related protein 2 antibodycerebral protein 7 antibodyH5 antibodyhCDCREL-2 antibodyHucep 7 antibodyMART antibodyPeanut-like protein 2 antibodyPNUTL2 antibodySEP4 antibodySEPT4 antibodySeptin-4 antibodyProtein information supplied by UniProt

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