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FabGennix/DRP1 Antibody/DRP1-101AP
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Descriptionbody { line-height:115%; font-family:Calibri; font-size:11pt }p { margin:0pt 0pt 10pt }table { margin-top:0pt; margin-bottom:10pt }.BalloonText { margin-bottom:0pt; line-height:normal; font-family:Tahoma; font-size:8pt }span.BalloonTextChar { font-family:Tahoma; font-size:8pt }span.Hyperlink { text-decoration:underline; color:#0000ff }.TableGrid { margin-bottom:0pt; line-height:normal }General InformationProductDRP1 Antibody DescriptionDynamin-related Protein 1 Antibody Verified ApplicationsELISA, ICC, IF, IHC, IP, WBHostRabbitSpecies Cross ReactivityD. Melanogaster, Human, Mouse, RatImmunogenSynthetic peptide within 450-490 on human DRP1 protein.Accession #GenBank: BAC06576.1Physical PropertiesQuantity100 µgVolume200 µlConcentration0.55-0.68 µg/µl in antibody stabilization bufferImmunoglobulinIgGClonalityPolyclonalStorage-20°C for long term storageApplication ProtocolELISA1:10,000Immunocytochemistry1:100Immunofluorescence1:100Immunohistochemistry1:100Immunoprecipitation1:200Western Blot1:450ProteinUniprot #Q8K1M6OverviewFunctions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism.Molecular FunctionGTP-binding, Lipid-binding, Nucleotide-bindingSubcellular LocationGolgi apparatus; Peripheral membrane protein; peroxisome; Mitochondrion outer membrane; Clathrin-coated pit; synaptic vesicle membraneExpressionExpressed in the cerebellum and in several regions of the cerebrum and diencephalonStructureHomotetramer; dimerizes through the N-terminal GTP-middle region of one molecule binding to the GED domain of another DNM1L molecule. Oligomerizes in a GTP-dependent manner to form membrane-associated tubules with a spiral pattern. Can also oligomerize to form multimeric ring-like structures.Alternative NomenclatureDLP1 antibodydnm1l antibodyDnm1p/Vps1p-like protein antibodydnml1 antibodyDRP1 antibodyDVLP antibodyDymple antibodyDynamin 1 like antibodyDynamin family member proline-rich carboxyl-terminal domain less antibodyDynamin like protein antibodyDynamin-like protein 4 antibodyDynamin-related protein 1 antibodyDYNIV 11 antibodyEMPF antibodyFLJ41912 antibodyHdynIV antibodyVPS1 antibodyProtein information supplied by UniProt

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