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FabGennix/DCC Antibody/DCCR-101AP
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Descriptionbody { line-height:115%; font-family:Calibri; font-size:11pt }p { margin:0pt 0pt 10pt }table { margin-top:0pt; margin-bottom:10pt }.BalloonText { margin-bottom:0pt; line-height:normal; font-family:Tahoma; font-size:8pt }.ListParagraph { margin-left:36pt; margin-bottom:10pt; line-height:115%; font-size:11pt }span.BalloonTextChar { font-family:Tahoma; font-size:8pt }span.FollowedHyperlink { text-decoration:underline; color:#800080 }span.Hyperlink { text-decoration:underline; color:#0000ff }.TableGrid { margin-bottom:0pt; line-height:normal }General InformationProductDCC AntibodyDescriptionAffinity Purified Netrin Receptor DCC Antibody Verified ApplicationsELISA, IP, WBHostRabbitSpecies Cross ReactivityHuman, Mouse, RatImmunogenSynthetic peptide taken within amino acid region 1330-1380 on rat DCC protein.Physical PropertiesQuantity100 µgVolume200 µlConcentration0.5-.70 µg/µl in antibody stabilization bufferFormAffinity PurifiedClonalityPolyclonalStorage-20°C for long term storageApplication ProtocolDB1:10,000ELISA1:10,000Immunoprecipitation1:200Western Blot1:500ProteinUniprot #P43146OverviewReceptor for netrin required for axon guidance; may trigger signaling for axon repulsion; acts as a dependence receptor required for apoptosis induction; tumor suppressor gene.Molecular Functionnetrin receptor activity; transcription coactivator activity; transmembrane signaling receptor activity; Developmental proteinSubcellular Locationaxon; cytosol; plasma membraneExpressionFound in axons of the central and peripheral nervous system;differentiated cell types of the intestineStructureBelongs to the immunoglobulin superfamily. DCC family; Contains 6 fibronectin type-III domains; Contains 4 Ig-like C2-type (immunoglobulin-like) domainsAlternative NomenclatureColorectal cancer related chromosome sequence 18 antibodyCRC 18 antibodyCRCR 1 antibodyDCC antibodyDeleted in colorectal cancer protein antibodyImmunoglobulin superfamily DCC subclass member 1 antibodyNetrin receptor DCC antibodyTumor suppressor protein DCC antibodyProtein information supplied by UniProt

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