首页 > BioXcell > BioXcell/InVivoMAb anti-mouse PD-L2 (B7-DC)/REGULAR: 5MG/BE0112-R005mg

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BioXcell/InVivoMAb anti-mouse PD-L2 (B7-DC)/REGULAR: 5MG/BE0112-R005mg

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BE0112-R005mg

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About InVivoMAb anti-rat β-2-MicroglobulinThe 4C9 monoclonal antibody reacts with rat beta 2 microglobulin (β2M) a 12 kDa component of MHC class I molecules. β-2-microglobulin, a non-membrane-anchored glycoprotein, noncovalently associates with the polymorphic heavy chain of MHC class I molecules to form the HLA class I antigen complex. β-2-microglobulin is expressed on all leukocytes, platelets, endothelial cells and epithelial cells and plays an essential role in mediating proper folding and expression of MHC class I molecules. The importance of β-2-microglobulin is illustrated by β-2-microglobulin knockout mice which show a normal distribution of T lymphocytes, but have no mature CD4 or CD8 T cells and are therefore defective in CD4 and CD8 T cell-mediated cytotoxicity. The 4C9 antibody recognizes rat β-2-microglobulin alone or complexed with FcRn heavy chains.InVivoMAb anti-rat β-2-Microglobulin SpecificationsIsotypeMouse IgG1Recommended Isotype Control(s)InVivoMAb mouse IgG1 isotype control, unknown specificity(BE0083)Recommended InVivoPure Dilution BufferInVivoPure pH 7.0 Dilution Buffer(IP0070)ImmunogenSoluble neonatal Fc receptor (FcRn)Endotoxin<2EU/mg (<0.002EU/μg)Determined by LAL gel clotting assayPurity>95%Determined by SDS-PAGEFormulationPBS, pH 7.0Contains no stabilizers or preservativesSterility0.2 μM filteredProductionPurified from tissue culture supernatant in an animal free facilityPurificationProtein GStorageThe antibody solution should be stored at the stock concentration at 4°C. Do not freeze.RRIDAB_10951294Molecular Weight150 kDa

Bio X Cell采用最先进的发酵技术；包括搅拌罐发酵罐和波包系统；我们的生产能力从5升到500升不等。

Bio X Cell提供从现有杂交瘤细胞系产生的抗体的生产和纯化服务。这些杂交瘤通常在客户的实验室中开发或在公共领域可用。

该服务包括在细胞培养物中发酵杂交瘤，通过离心收获细胞培养上清液以及通过30 kDa超滤浓缩。通过蛋白A或G亲和色谱进行纯化。将纯化的抗体透析到PBS中并过滤除菌。我们所有定制产品的内毒素水平<2EU / mg。我们还提供冻结细胞系，现场细胞系存储和MAP测试的额外费用。