首页 > BioXcell > BioXcell/InVivoMAb anti-mouse CD4/AMOUNT GREATER THAN 100 MG: (QUOTE ONLY)/BE0119-CUST

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BioXcell/InVivoMAb anti-mouse CD4/AMOUNT GREATER THAN 100 MG: (QUOTE ONLY)/BE0119-CUST

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About InVivoMAb anti-rat CD4The OX-38 monoclonal antibody reacts with the rat CD4. The CD4 antigen is a 55 kDa cell surface type I membrane glycoprotein belonging to the immunoglobulin superfamily. CD4 acts as a co-receptor which in cooperation with the T cell receptor (TCR) interacts with class II MHC molecules displayed by antigen presenting cells (APC). CD4 is expressed by the majority of thymocytes, most helper T cells, a subset of NK-T cells and weakly by dendritic cells and macrophages. CD4 plays an important role in the development of T cells and is required for mature T cells to function optimally. The OX-38 antibody has been reported to deplete CD4+ T cells in vivo.InVivoMAb anti-rat CD4 SpecificationsIsotypeMouse IgG2a, κRecommended Isotype Control(s)InVivoMAb mouse IgG2a isotype control, unknown specificity(BE0085)Recommended InVivoPure Dilution BufferInVivoPure pH 7.0 Dilution Buffer(IP0070)ImmunogenRat thymocyte glycoproteinsReported Applicationsin vivo CD4+ T cell depletionFlow cytometryEndotoxin<2EU/mg (<0.002EU/μg)Determined by LAL gel clotting assayPurity>95%Determined by SDS-PAGEFormulationPBS, pH 7.0Contains no stabilizers or preservativesSterility0.2 μM filteredProductionPurified from tissue culture supernatant in an animal free facilityPurificationProtein ARRIDAB_2736988Molecular Weight150 kDaStorageThe antibody solution should be stored at the stock concentration at 4°C. Do not freeze.

Bio X Cell采用最先进的发酵技术；包括搅拌罐发酵罐和波包系统；我们的生产能力从5升到500升不等。

Bio X Cell提供从现有杂交瘤细胞系产生的抗体的生产和纯化服务。这些杂交瘤通常在客户的实验室中开发或在公共领域可用。

该服务包括在细胞培养物中发酵杂交瘤，通过离心收获细胞培养上清液以及通过30 kDa超滤浓缩。通过蛋白A或G亲和色谱进行纯化。将纯化的抗体透析到PBS中并过滤除菌。我们所有定制产品的内毒素水平<2EU / mg。我们还提供冻结细胞系，现场细胞系存储和MAP测试的额外费用。