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Hello Bio/Quinolinic acid/HB0544/1g
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产品说明
Product overview Name Quinolinic acid Short description Endogenous NMDA receptor agonist Biological description Endogenous NMDA receptor agonist. Shows no activation at GluN1 and GluN2C subunit containing receptors. Displays neurotoxin and pro-inflammatory properties. Biological action Agonist Our products in action Submit Your Citation NowProperties Chemical name Pyridine-2,3-dicarboxylic acid Molecular Weight 167.12 Chemical structure Molecular Formula C7H5NO4 CAS Number 89-00-9Storing and Using Your Product Storage instructions room temperature Solubility overview soluble in NaOH(aq) (50mM, 1eq. NaOH) Important This product is for RESEARCH USE ONLY and is not intended for therapeutic or diagnostic use. Not for human or veterinary use.References for Quinolinic acidQuinolinic acid, the inescapable neurotoxin. Guillemin GJ (2012) FEBS J 279(8) : 1356-65. PubMedID: 22248144 The endogenous agonist quinolinic acid and the non endogenous homoquinolinic acid discriminate between NMDAR2 receptor subunits. de Carvalho LP et al (1996) Neurochem Int 28(4) : 445-52. PubMedID: 8740453 Quinolinic acid and kynurenine pathway metabolism in inflammatory and non-inflammatory neurological disease. Heyes MP et al (1992) Brain 115 ( Pt 5) : 1249-73. PubMedID: 1422788 Quinolinic acid: an endogenous neurotoxin with multiple targets. Lugo-Huitrón R et al (2013) Oxid Med Cell Longev 2013 : 104024 PubMedID: 24089628

Hello Bio是由一群经验丰富的科学家和化学家们创立的充满活力的生物企业,总部位于英国布里斯托尔,在美国普林斯顿设有分公司,主旨在于提供质优价廉的生命科学研究工具,主要产品线为小分子化合物,如激动剂、拮抗剂、抑制剂等,部分产品价格甚至低至其他供应商的50%


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各种信号通路抑制剂、激动剂




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novel selective GRK2/3 inhibitor,  NMDA antagonist D-AP5, Group I mGlu agonist (S)-3,5-DHPG, and GABAA antagonist SR 95531.




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ROCK inhibitor Y-27632,  SB 431542 DAPT.



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