Description
PenicillinGisahydrophobicβ-lactamantibioticthatdisplaysantibacterialefficacyagainstgrampositivebacteria.PenicillinGismoreactivethanpenicillinVagainstgramnegativebacteriabutexhibitspoororalabsorptionkineticsandmustbeadmiNISTeredbyparenteralinjection.PenicillinGinhibitscellwallsynthesisanddoesnotdisplayeffectiveinhibitionofβ-lactamase-producingbacteria.PenicillinGmayinduceopenchannelorcompetitiveblockofneuromuscularnicotinicacetylcholinereceptors(nAChRs).
References
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