首页 > Biosensis > Biosensis/Mouse polyclonal antibody to human Siah-1/M-867-50/50 µL

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Biosensis/Mouse polyclonal antibody to human Siah-1/M-867-50/50 µL

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M-867-50

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4000-520-616

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DescriptionSiah-1isamemberoftheseveninabsentiahomolog(SIAH)family.ItisaE3ubiquitin-proteinligasethatmediatesubiquitinationandsubsequentproteasomaldegradationoftargetproteins,includingmanyproteinsinvolvedintranscriptionregulation,acellsurfacereceptor(DCC),cytoplasmicsignaltransductionmolecules,anantiapoptoticprotein(BAG1),amicrotubulemotorprotein(KIF22),aproteininvolvedinsynapticvesiclefunctioninneurons(SYP)andastructuralprotein.ConsequentlySiah-1isinvolvedinmanycellularprocessessuchasapoptosis,tumorsuppression,cellcycle,axonguidance,transcriptionregulation,spermatogenesis,andTNF-alphasignaling.Itispredominantlyacytoplasmicproteinbutisalsopartiallyanuclearprotein.Itiswidelyexpressedatlowlevelsandisdown-regulatedinadvancedhepatocellularcarcinomas.BatchNo.SeeproductlabelUnitsize50µLAntigenPartialrecombinanthumanSiah-1(aminoacids1-110)withaGSTtag.OtherNamesE3ubiquitin-proteinligaseSIAH1;Seveninabsentiahomolog1;Siah-1a;SIAH1;HUMSIAHAccessionSIAH1_HUMANProducedinMouseApplicationsThisantibodyisrecommendedforELISA.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.Cross-reactivityHuman.Otherspecieshavenotbeentested.BlastitToseethesharedidentitybetweendifferentspeciesorotherproteins,followthelinkintheAccessionfield,selectthesequencethatyouareinterestedinandcopyandpasteitHEREandblast/formatit.FormLiquidwith50%glycerolStorageKeepaliquotsat-20ºCforhigherstABIlity.Avoidrepetitivefreeze/thawcycles.ExpiryDate12monthsafterpurchase

Biosensis是一家由生命科学家和商业团队组成的公司，致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验，并在生命科学研究和诊断市场的生命科学抗体，试剂和试剂盒的商业化方面拥有50多年的经验。