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Biosensis/Rabbit antibody to Saporin: whole serum/R-025-100/100 µl
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DescriptionSaporinisaribosome-inactivatingprotein(RIP)oftypeI.ThismonomericRNAN-glycosidasepurifiedfromseedsoftheplantSaponariaofficinalisalsoknownasSoapwort,iscapableofspecificdepurinationofeukaryoticribosomesthusarrestingproteinsynthesis.NoligandhasbeenidentifiedinsaporinhenceitsinABIlitytotransversethecellmembrane.Duetoitstoxicityandstabilityofthestructure,saporinhasprovenextremelyusefulforconstructionofimmunotoxins.Theexpectedmolecularweightofthepurifiedsaporinis29.5kDa.BatchNo.SeeproductlabelUnitsize100µlAntigenSaporin,wholemoleculeOtherNamesSaponariaofficinalis;CommonsoapwortAccessionRIP6_SAPOFProducedinRabbitPurityWholeserumApplicationsIHC,Immunofluorescence,ELISA,WesternBlot.Adilutionof1:200to1:2000isrecommended.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.SpecificityConfirmedtoreactwithpurifiedsaporin.Cross-reactivityNocross-reactivitywithothermoleculeshasbeenreported.FormLyophilisedReconstitutionReconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial.StorageAfterreconstitutionkeepaliquotsat-20ºCforahigherstability,andat4ºCwithanappropriateantibacterialagent.Avoidrepetitivefreeze/thawcycles.Glycerol(1:1)maybeaddedforanadditionalstability.ExpiryDate12monthsafterpurchaseReferences1.Stirpe,F.etal(1983)BiochemJ216,617-6252.Tazzari,P.L.etal(1988)CancerImmunolImmunother.26,231-2363.Strocchi,P.etal(1992)JImmunolMethods.155,57-634.Savino,C.etal(2000)FEBSLett.470,239-2435.Barbieri,L.etal(2000)JBiochem(Tokyo).128,883-8896.Savino,C.etal(1998)ActaCrystallogrDBiolCrystallogr.54,636-6387.Santanche,S.etal(1997)BiochemBiophysResCommun.234,129-132

Biosensis是一家由生命科学家和商业团队组成的公司,致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验,并在生命科学研究和诊断市场的生命科学抗体,试剂和试剂盒的商业化方面拥有50多年的经验。

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