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Biosensis/Rabbit antibody to human CDNF (conserved dopamine neurotrophic factor)/R-1674-100/100 ug
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DescriptionCDNF(conserveddopamineneurotrophicfactor)isatrophicfactorformidbraindopamineneuronsinvivo.Itpreventsthe6-OHDA-(Lindholmetal.20007;Voutilainenetal.,2011)andMPTP-induceddegeneration(Airavaaraetal.,2012)ofdopamineneuronsinrodentmodelsofParkinsonsdisease.WhenadmiNISTeredafter6-OHDAorMPTPlesioningitrestoresthedopaminergicfunctionandpreventsdegenerationofdopamineneuronsinsubstantianigraparscompacta.RelatedproductsM-1676-100;M-1677-100;BEK-2212-2PELISABatchNo.SeeproductlabelUnitsize100ugAntigenRecombinanthumanCDNFproteinproducedusingCHO-basedcellline.Purifiedfromcellculturesupernatant.Sequencewholemolecule,UniprotQ49AH0AntibodyTypePolyclonalIsotypeIgGOtherNamesARMETL1AccessionQ49AH0ProducedinRabbitMolecularWeight~15kDareducinggel,matureformsPurityAffinitypurifiedApplicationsWesternblot(WB)atasuggesteddilutionof1:6,0001:10,000.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.SpecificityCDNF(conserveddopamineneurotrophicfactor)SpeciesAgainstHumanFormConcentratedammoniumsulphateinPBSpH7.4containingnopreservatives.ReconstitutionStoreantibodystocksolutionat+4°Cuponreceipt.DONOTFREEZE.Thisproductisan(NH4)2SO4precipitate.Touse,mixwellbypipettingorvortexinggentlyprioruse,thenwithdrawthedesiredamountofantibodystocksolutionanddiluteintoyourantibodydilutionbufferandusenormally.Alternatively,materialcanbecentrifugedat10Kxgfor5minutesandtheliquidsulfatesolutioncarefullyremoved.ThenprecipitatedantibodycanberesUSPendedin0.1MP,250mMNaCL,pH7.4solution.Thesolutionshouldthenbedividedintoworkingaliquotsandstoredat-80°Cuntilused.Preventmultiplefreezethawcyclesofaliquotsforbestproductlife.StorageStoreat+4°Cuponreceipt;Donotfreeze.Seereconstitutioninstructionsforhandlinginformation.ExpiryDate12monthsafterpurchase
Biosensis是一家由生命科学家和商业团队组成的公司,致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验,并在生命科学研究和诊断市场的生命科学抗体,试剂和试剂盒的商业化方面拥有50多年的经验。
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