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DescriptionGPx-PbelongstotheglutathioneperoxidasefamilywhichareresponsIBLeforthedetoxificationofhydrogenperoxide.Itprotectscellsandenzymesfromoxidativedamage,bycatalyzingthereductionofhydrogenperoxide,lipidperoxidesandorganichydroperoxide,byglutathione.GPx-Pissecretedinplasmaandexistsasahomotetramer.BatchNo.SeeproductlabelUnitsize100µlAntigenAsyntheticpeptide(FEKGDVNGEKEQKFYTFLKN)correspondingtotheaminoacids135-154ofhumanglutathioneperoxidase3(GPx-P)conjugatedtodiphtheriatoxinhasbeenusedastheimmunogen.Thepeptideishomologouswiththecorrespondingsequencederivedfromglutathioneperoxidase3(GPx-P)proteininmouse,rat,orangutanandbovine.OtherNamesExtracellularglutathioneperoxidase;GPx-P;GSHPx-3;GPx-3;Plasmaglutathioneperoxidase;GSHPx-P;GPX3;GPXPAccessionGPX3_HUMANProducedinRabbitPurityWholeserumApplicationsIHC,only.Adilutionof1:1000to1:5000isrecommendedforimmunohistochemistrydependingondetectionmethodbutenduserwillneedtodeterminedilutiontosuitapplication.Antigenretrievalisrecommended.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.SpecificityThisantibodyhasbeenshowntobespecificforglutathioneperoxidase3protein(GPx-P)throughstainingandblockingstudies.Cross-reactivityHumanandrat,otherspecieshavenotyetbeenested.BlastitIfyouwouldliketousethisproductinanotherspeciesotherthanthosespecifiedhere,ortoseethesharedidentitybetweentheimmunogenusedhereindifferentspeciesand/orothermolecules,simplycopytheimmunogen(fromtheImmunogenfield)andpasteitHEREandblast/formatit.Notethat,antiseraraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptideie,onlyonesingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.Regardless,youcanalwayscontactusifyouneedassistancewiththis.FormLyophilisedReconstitutionReconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial.StorageAfterreconstitutionkeepaliquotsat-20ºCforahigherstABIlity,andat4ºCwithanappropriateantibacterialagent.Avoidrepetitivefreeze/thawcycles.ExpiryDate12monthsafterpurchaseReferences1.TakahashiK,etal.J.Biochem.108:145-148(1990).2.ChuF.-F,etal.Blood79:3233-3238(1992).
Biosensis是一家由生命科学家和商业团队组成的公司,致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验,并在生命科学研究和诊断市场的生命科学抗体,试剂和试剂盒的商业化方面拥有50多年的经验。
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