首页 > Biosensis > Biosensis/Rabbit antibody to mouse superoxide dismutase (SOD1; 24-36): whole serum/R-126-100/100 µl

提醒：代购产品，无质量问题不接受退换货，下单前请仔细核对信息。下单后请及时联系客服核对商品价格，订单生效后再付款。

Biosensis/Rabbit antibody to mouse superoxide dismutase (SOD1; 24-36): whole serum/R-126-100/100 µl

价格：

登录查看

自营商城

解放采购

正品保障

及时交付

厂家直采

一站服务

货号：

R-126-100

品牌：

Biosensis

会员服务：

尊享会员价

贵宾专线

运费优惠

闪电退款

福利优惠

上门换新

友情提示

以上价格仅为参考，请联系客服询价。

免费咨询热线

4000-520-616

产品说明

DescriptionFUNCTION:DestroysrADIcalswhicharenormallyproducedwithinthecellsandwhicharetoxictoBIOLOGicalsystems.CATALYTICACTIVITY:2superoxide+2H+=O2+H2O2.COFACTOR:Binds1copperionpersubunit.COFACTOR:Binds1zincionpersubunit.SUBUNIT:Homodimer.SUBCELLULARLOCATION:Cytoplasm.DISEASE:DefectsinSOD1arethecauseoffamilialamyotrophiclateralsclerosis(FALS);alsocalledamyotrophiclateralsclerosis1(ALS1orALS).ALSisadegenerativedisorderofmotorneuronsinthecortex,brainstemandspinalcord.ALSischaracterizedbymuscularweaknessandatrophybeginninginthehandsandspreadingtotheforearmsandlegs.MusclefasciculationsarecommonlyvisIBLe.Sensoryabnormalitiesareabsent.Deathusuallyoccurswithin2to5years.ALSissometimesreferredtoasLouGehrigdiseaseafterthefamousAmericanbaseballplayerwhowasdiagnosedwiththedisorder.FALS,thefamilialformofALS,accountsforabout10%ofthecasesandistransmittedinanautosomaldominantmanner.ThemeanageatonsetofFALSis45years.MISCELLANEOUS:Zincbindingpromotesdimerization.SIMILARITY:BelongstotheCu-Znsuperoxidedismutasefamily.BatchNo.SeeproductlabelUnitsize100µlAntigenAsyntheticpeptide(ASGEPVVLSGQIT)aspartofmousesuperoxidedismutase(SOD1)protein(aa:24-36)conjugatedtodiphtheriatoxoidOtherNamesSuperoxidedismutase[Cu-Zn];SOD1AccessionSODC_MOUSEProducedinRabbitPurityWholeserumApplicationsWB.Adilutionof1:500to1:1000isrecommendedforthisapplication.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.SpecificitySpecificitywasconfirmedbywesternblotdetectingmousesuperoxidedismutase(SOD1).Cross-reactivityThisantiserumisknowntoreactwithmouseandratsuperoxidedismutase(SOD1)protein.BlastitIfyouwouldliketousethisproductinanotherspeciesotherthanthosespecifiedhere,ortoseethesharedIDbetweentheimmunogenusedhereindifferentspeicesand/orothermolecules,simplycopytheimmunogen(fromtheImmunogenfield)andpasteitHEREandblast/formatit.Notethat,antiseraraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptideie,onlyonesingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.Regardless,youcanalwayscontactusifyouneedassistancewiththis.FormLyophilisedReconstitutionReconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial.StorageAfterreconstitutionkeepaliquotsat-20ºCforahigherstABIlity,andat4ºCwithanappropriateantibacterialagent.Glycerol(1:)maybeaddedforanadditionalstability.Avoidrepetitivefreeze/thawcycles.SpecificReferencesParkKHetal.(2013)PostnatalmusclemodificationbymyogenicfactorsmodulatesneuropathologyandsurvivalinanALSmousemodel.NatCommun.2013;4:2906.GeneralReferences1.JabuschJ.R,etal.Biochemistry19:2310-2316(1980).2.LevanonD,etal.EMBOJ.4:77-84(1985).3.HallewellR.A,etal.NucleicAcidsRes.13:2017-2034(1985).4.ShermanL,etal.Proc.Natl.Acad.Sci.U.S.A.80:5465-5469(1983).5.KajiharaJ,etal.J.Biochem.104:851-854(1988).6.AlexanderM.D,etal.Ann.Neurol.52:680-683(2002).7.GelleraC,etal.Neuromuscul.Disord.11:404-410(2001).8.MurakamiT,etal.J.Neurol.Sci.189:45-47(2001).9.PencoS,etal.Neurology53:404-406(1999).10.MoritaM,etal.Neurosci.Lett.205:79-82(1996).11.Bartlett,etal.J.NeuroscienceMethods.98(1):63-7(2000)

Biosensis是一家由生命科学家和商业团队组成的公司，致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验，并在生命科学研究和诊断市场的生命科学抗体，试剂和试剂盒的商业化方面拥有50多年的经验。