首页 > Biosensis > Biosensis/Rabbit polyclonal antibody to human Cyclooxygenase-1 (35-52): Affinity purified/R-1599-100/100 µg

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Biosensis/Rabbit polyclonal antibody to human Cyclooxygenase-1 (35-52): Affinity purified/R-1599-100/100 µg

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R-1599-100

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DescriptionCyclooxygenase(COX)isanimportantenzymeintheconversionofarachidonicacidtoProstaglandinH2,theprecursoroftheseries-2prostanoids.Atleast3splicevariantshavebeenfound(COX-1,COX-2andCOX-3).COX-1isconstitutivelyexpressedinmostcelltypesandisinducedaspartoftheinflammatoryresponsebycytokinesaswellasbygrowthfactorssuchasEGFandPDGF.BatchNo.Seeproductlabel.Unitsize100µgAntigenAsyntheticpeptidecorrespondingtoaregion(35-52aa)fromhumanCyclooxygenase-1.Toenhancetheimmunologicalresponse,thispeptidewascoupledtocarrierproteinBSA.OtherNamesProstaglandinG/Hsynthase1;Cyclooxygenase-1;COX-1;Prostaglandin-endoperoxidesynthase1;ProstaglandinH2synthase1;PGHsynthase1;PGHS-1;PHS1;PTGS1;COX1;AccessionP23219PGH1_HUMAN;ProducedinRabbitPurityAffinitypurifiedonantigencolumnApplicationsImmunohistochemistry(IHC)andWesternBlotting(WB).Aconcentrationof0.1-0.5µg/mlisrecommendedforWB.HumanCOX-1(long)hasapredictedlengthof599residuesandMWof69kDa.Aconcentrationof0.5-1.0µg/mlisrecommendedforIHCtodetecttheproteininformalinfixedandparaffinembeddedtissues.Heatmediatedantigenretrievalisrecommended.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.Cross-reactivityHuman(WB,IHC);rat(WB);mouse(WB);FormLyophilizedwith5mgBSA,0.9mgNaCl,0.2mgNa2HPO4,0.05mgThimerosal,0.05mgNaN3addedaspreservativeReconstitutionReconstitutein100µlofsteriledistilledwatertoachieveanantibodyconcentrationof1mg/ml.Centrifugetoremoveanyinsolublematerial.StorageAtleast12monthsafterpurchaseat2-4°C(lyophilizedformulations).Afterreconstitution,aliquotandstoreat-20°CforahigherstABIlity.Avoidfreeze-thawcyclesExpiryDate12monthsafterpurchase

Biosensis是一家由生命科学家和商业团队组成的公司，致力于为全球学术界和工业界的研究人员提供支持。该团队在基础和应用生命科学研究方面拥有超过100年的经验，并在生命科学研究和诊断市场的生命科学抗体，试剂和试剂盒的商业化方面拥有50多年的经验。