Description:5-HT1B/1AagoNISTChemicalName:5-Methoxy-3-(1,2,5,6-tetrahydro-4-pyridinyl)-1H-indolehemisuccinatePurity:≥99%(HPLC)BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferencesBiologicalActivityPotent5-HT1A/1Bandmoderate5-HT2Cagonistthatmayalsorelease5-HT.Centrallyactivefollowingsystemicadministration.TechnicalDataM.Wt287.34FormulaC14H16N2O.½C4H6O4StorageStoreatRTPurity≥99%(HPLC)CASNumber66611-27-6PubChemID3050530InChIKeyBNYJLRQAWCQJOM-UHFFFAOYSA-NSmilesOC(=O)CCC(O)=O.COC1=CC=C2NC=C(C2=C1)C1=CCNCC1.COC1=CC=C2NC=C(C2=C1)C1=CCNCC1Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.AllTocrisproductsareintendedforlaboratoryresearchuseonly.SolubilityDataSolventMaxConc.mg/mLMaxConc.mMSolubilityDMSO14.3750water8.6230PreparingStockSolutionsThefollowingdataisbasedontheproductmolecularweight287.34.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.Concentration/SolventVolume/Mass1mg5mg10mg1mM3.48mL17.4mL34.8mL5mM0.7mL3.48mL6.96mL10mM0.35mL1.74mL3.48mL50mM0.07mL0.35mL0.7mLMolarityCalculatorMolarityCalculatorCalculatethemass,volume,orconcentrationrequiredforasolution.ReconstitutionCalculatorReconstitutionCalculatorDilutionCalculatorDilutionCalculatorCalculatethedilutionrequiredtoprepareastocksolution.ProductDatasheetsCertificateofAnalysis/ProductDatasheetSafetyDatasheetSelectanotherlanguage:EnglishGermanFrenchSpanishViewSDSReferencesReferencesarepublicationsthatsupporttheproducts'biologicalactivity.Gudermannetal(1993)HumanS31SEROtoninreceptorcloneencodesa5-hydroxytryptamine1E-likeserotoninreceptor.Mol.Pharmacol.43412PMID:8450834TomkinsandO'Neill(2000)Effectof5-HT1Breceptorligandsonself-administrationofethanolinanoperantprocedureinrats.Pharmacol.Biochem.Behav.66129PMID:10837852Guillaumeetal(1987)Synthesisof3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indolesandstudyoftheirserotonergicandantidopaminergicproperties.Eur.J.Med.Chem.2233PMID:Keywords:RU24969hemisuccinate,supplier,5-HT1B/1A,agonists,Serotonin,Receptors,RU24969,hemisuccinate,C14H16N2O.0.5C4H6O4,5-HT1A,Receptors,5-HT1A,Receptors,TocrisBioscience
Tocris Bioscience是一家专卖生命科学研究chemicals, peptides and antibodies的知名品牌，其产品也广为各大药厂、大学、研究机构，超过五万名科学研究者所采用。 目前，產品內容已超過一千六百種以上，並每年持續不斷的增加新的產品。目前，产品内容已超过一千六百种以上，并每年持续不断的增加新的产品。
Tocris bioscience是位于英国布里斯托尔（Bristol）的高品质试剂提供商，共有2000多种产品，主要集中在神经科学和信号传导领域，产品类型包括小分子、多肽、抗体、配体和化合物筛选文库等，主要产品包括GPCR ligands，神经传递素，离子通道调控剂，信号通路抑制剂等，这些产品被广泛选择性地用于阻断或激活生物学通路。Tocris是世界上神经科学研究领域无可争议的领导者，其生产的影响神经系统的化学物质被多次引用，这些物质很多都来自Jeff Watkins（Tocris 的创立人）在Bristol大学原创性的研究工作。
Tocris Bioscience的主要产品包括：
Small Molecules
Peptides
Aptamers
Controlled Substances
Compound Libraries
DREADD Ligands
Fluorescent Imaging
Ligand Sets
Optopharmacology
Reagents
Toxins
按照研究领域细分：
Cancer
Cardiovascular System
Endocrinology
Immunology
Neuroscience
Pain & Inflammation
Respiratory System
