Description:Potent,highlyselectiveCB1agoNISTAlternativeNames:Arachidonyl-2'-chloroethylamideChemicalName:N-(2-Chloroethyl)-5Z,8Z,11Z,14Z-eicosatetraenamideBIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferencesBiologicalActivityPotentandhighlyselectiveCB1receptoragonist(Ki=1.4nM).Displays>1400-foldselectivityoverCB2receptors.Activeinvivo.TechnicalDataM.Wt365.99FormulaC22H36ClNOStorageStoreat-20°CCASNumber220556-69-4PubChemID5311007InChIKeyGLGAUBPACOBAMV-DOFZRALJSA-NSmilesO=C(NCCCl)CCCC=C/CC=C/C/C=CC/C=CCCCCCThetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.AllTocrisproductsareintendedforlaboratoryresearchuseonly.SolubilityDataSolubilitySolubleinethanol(suppliedpre-dissolvedinanhydrousethanol,5mg/ml)PreparingStockSolutionsThefollowingdataisbasedontheproductmolecularweight365.99.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.Concentration/SolventVolume/Mass1mg5mg10mg1mM2.73mL13.66mL27.32mL5mM0.55mL2.73mL5.46mL10mM0.27mL1.37mL2.73mL50mM0.05mL0.27mL0.55mLMolarityCalculatorMolarityCalculatorCalculatethemass,volume,orconcentrationrequiredforasolution.ReconstitutionCalculatorReconstitutionCalculatorDilutionCalculatorDilutionCalculatorCalculatethedilutionrequiredtoprepareastocksolution.ProductDatasheetsCertificateofAnalysis/ProductDatasheetSafetyDatasheetSelectanotherlanguage:EnglishGermanFrenchSpanishViewSDSReferencesReferencesarepublicationsthatsupporttheproducts'biologicalactivity.Hillardetal(1999)SynthesisandcharacterizationofpotentandselectiveagonistsoftheneuronalcannABInoidreceptor(CB1).J.Pharmacol.Exp.Ther.2891427PMID:10336536Pertwee(1999)Pharmacologyofcannabinoidreceptorligands.Curr.Med.Chem.6635PMID:10469884Pateletal(2001)CannabinoidCB1receptoragonistsproducecerebellardysfunctioninmice.J.Pharmacol.Exp.Ther.297629PMID:11303052Keywords:ACEA,supplier,Potent,selective,CB1,agonists,Cannabinoids,Receptors,cb1r,Arachidonyl-2"-chloroethylamide,CB1,Receptors,CB1,Receptors,TocrisBioscience
Tocris Bioscience是一家专卖生命科学研究chemicals, peptides and antibodies的知名品牌，其产品也广为各大药厂、大学、研究机构，超过五万名科学研究者所采用。 目前，產品內容已超過一千六百種以上，並每年持續不斷的增加新的產品。目前，产品内容已超过一千六百种以上，并每年持续不断的增加新的产品。
Tocris bioscience是位于英国布里斯托尔（Bristol）的高品质试剂提供商，共有2000多种产品，主要集中在神经科学和信号传导领域，产品类型包括小分子、多肽、抗体、配体和化合物筛选文库等，主要产品包括GPCR ligands，神经传递素，离子通道调控剂，信号通路抑制剂等，这些产品被广泛选择性地用于阻断或激活生物学通路。Tocris是世界上神经科学研究领域无可争议的领导者，其生产的影响神经系统的化学物质被多次引用，这些物质很多都来自Jeff Watkins（Tocris 的创立人）在Bristol大学原创性的研究工作。
Tocris Bioscience的主要产品包括：
Small Molecules
Peptides
Aptamers
Controlled Substances
Compound Libraries
DREADD Ligands
Fluorescent Imaging
Ligand Sets
Optopharmacology
Reagents
Toxins
按照研究领域细分：
Cancer
Cardiovascular System
Endocrinology
Immunology
Neuroscience
Pain & Inflammation
Respiratory System
