Description:OpioidreceptorligandChemicalName:[5α,7α(S)]-17-(Cyclopropylmethyl)-α-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α-methyl-6,14-ethenomorphinan-7-methanolhydrochloridePurity:≥99%(HPLC)BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferencesBiologicalActivityORL1receptoragoNISTthatalsodisplaysmixedantagonist/partialagonistactivityatκ,δandμ-opioidreceptors.TechnicalDataM.Wt504.1FormulaC29H41NO4.HClStorageStoreatRTPurity≥99%(HPLC)CASNumber53152-21-9PubChemID9848989InChIKeyUAIXRPCCYXNJMQ-HPRIMLMLSA-NSmilesOC1=CC=C3C2=C1O[C@@H]([C@@]7(OC)[C@]([C@@](C)(C(C)(C)C)O)([H])C4)[C@]52[C@@]4(CC7)[C@H](N(CC6CC6)CC5)C3.ClThetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.AllTocrisproductsareintendedforlaboratoryresearchuseonly.SolubilityDataSolventMaxConc.mg/mLMaxConc.mMSolubilityethanol25.250water12.625PreparingStockSolutionsThefollowingdataisbasedontheproductmolecularweight504.1.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.Concentration/SolventVolume/Mass1mg5mg10mg1mM1.98mL9.92mL19.84mL5mM0.4mL1.98mL3.97mL10mM0.2mL0.99mL1.98mL50mM0.04mL0.2mL0.4mLMolarityCalculatorMolarityCalculatorCalculatethemass,volume,orconcentrationrequiredforasolution.ReconstitutionCalculatorReconstitutionCalculatorDilutionCalculatorDilutionCalculatorCalculatethedilutionrequiredtoprepareastocksolution.ProductDatasheetsCertificateofAnalysis/ProductDatasheetSafetyDatasheetSelectanotherlanguage:EnglishGermanFrenchSpanishViewSDSReferencesReferencesarepublicationsthatsupporttheproducts'biologicalactivity.Wnendtetal(1999)Agonisteffectofbuprenorphineinanociceptin/OFQreceptor-triggeredreportergeneassay.Mol.Pharmacol.56334PMID:10419552Tzschentke(2002)Behavioralpharmacologyofbuprenorphine,withafocusonpreclinicalmodelsofrewardandaddiction.Psychopharmacology1611PMID:11967625Keywords:Buprenorphinehydrochloride,supplier,Opioids,receptors,ligands,Receptors,Miscellaneous/Non-selective,Opioids,Miscellaneous/Non-selective,Opioids,TocrisBioscience
Tocris Bioscience是一家专卖生命科学研究chemicals, peptides and antibodies的知名品牌，其产品也广为各大药厂、大学、研究机构，超过五万名科学研究者所采用。 目前，產品內容已超過一千六百種以上，並每年持續不斷的增加新的產品。目前，产品内容已超过一千六百种以上，并每年持续不断的增加新的产品。
Tocris bioscience是位于英国布里斯托尔（Bristol）的高品质试剂提供商，共有2000多种产品，主要集中在神经科学和信号传导领域，产品类型包括小分子、多肽、抗体、配体和化合物筛选文库等，主要产品包括GPCR ligands，神经传递素，离子通道调控剂，信号通路抑制剂等，这些产品被广泛选择性地用于阻断或激活生物学通路。Tocris是世界上神经科学研究领域无可争议的领导者，其生产的影响神经系统的化学物质被多次引用，这些物质很多都来自Jeff Watkins（Tocris 的创立人）在Bristol大学原创性的研究工作。
Tocris Bioscience的主要产品包括：
Small Molecules
Peptides
Aptamers
Controlled Substances
Compound Libraries
DREADD Ligands
Fluorescent Imaging
Ligand Sets
Optopharmacology
Reagents
Toxins
按照研究领域细分：
Cancer
Cardiovascular System
Endocrinology
Immunology
Neuroscience
Pain & Inflammation
Respiratory System
