Description:Highaffinity,selectiveCB2agoNISTChemicalName:N-Cyclohexyl-7-chloro-1-[2-(4-morpholinyl)ethyl]quinolin-4(1H)-one-3-carboxamidePurity:≥99%(HPLC)BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferencesBiologicalActivityHighaffinityandselectiveCB2receptoragonist;Kivaluesare3.3and>1000nMforCB2andCB1receptorsrespectively.TechnicalDataM.Wt417.93FormulaC22H28ClN3O3StorageStoreatRTPurity≥99%(HPLC)CASNumber913534-05-1PubChemID16086891InChIKeyMFKWLGOHFQBVAA-UHFFFAOYSA-NSmilesClC1=CC=C2C(N(CCN3CCOCC3)C=C(C(NC4CCCCC4)=O)C2=O)=C1Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.AllTocrisproductsareintendedforlaboratoryresearchuseonly.SolubilityDataSolventMaxConc.mg/mLMaxConc.mMSolubilityDMSO2.095mMwithgentlewarmingPreparingStockSolutionsThefollowingdataisbasedontheproductmolecularweight417.93.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.Concentration/SolventVolume/Mass1mg5mg10mg1mM2.39mL11.96mL23.93mL5mM0.48mL2.39mL4.79mL10mM0.24mL1.2mL2.39mL50mM0.05mL0.24mL0.48mLMolarityCalculatorMolarityCalculatorCalculatethemass,volume,orconcentrationrequiredforasolution.ReconstitutionCalculatorReconstitutionCalculatorDilutionCalculatorDilutionCalculatorCalculatethedilutionrequiredtoprepareastocksolution.ProductDatasheetsCertificateofAnalysis/ProductDatasheetSafetyDatasheetSelectanotherlanguage:EnglishGermanFrenchSpanishViewSDSReferencesReferencesarepublicationsthatsupporttheproducts'biologicalactivity.Maneraetal(2006)Design,synthesis,andbiologicalevaluationofnew1,8-naphthyridin-4(1H)-on-3-carboxamideandquinolin-4(1H)-on-3-carboxamidederivativesasCB2selectiveagonists.J.Med.Chem.495947PMID:17004710Keywords:CB65,supplier,High,affinity,selective,CB2,agonists,cannABInoids,Receptors,CB65,cb2r,CB2,Receptors,CB2,Receptors,TocrisBioscience
Tocris Bioscience是一家专卖生命科学研究chemicals, peptides and antibodies的知名品牌，其产品也广为各大药厂、大学、研究机构，超过五万名科学研究者所采用。 目前，產品內容已超過一千六百種以上，並每年持續不斷的增加新的產品。目前，产品内容已超过一千六百种以上，并每年持续不断的增加新的产品。
Tocris bioscience是位于英国布里斯托尔（Bristol）的高品质试剂提供商，共有2000多种产品，主要集中在神经科学和信号传导领域，产品类型包括小分子、多肽、抗体、配体和化合物筛选文库等，主要产品包括GPCR ligands，神经传递素，离子通道调控剂，信号通路抑制剂等，这些产品被广泛选择性地用于阻断或激活生物学通路。Tocris是世界上神经科学研究领域无可争议的领导者，其生产的影响神经系统的化学物质被多次引用，这些物质很多都来自Jeff Watkins（Tocris 的创立人）在Bristol大学原创性的研究工作。
Tocris Bioscience的主要产品包括：
Small Molecules
Peptides
Aptamers
Controlled Substances
Compound Libraries
DREADD Ligands
Fluorescent Imaging
Ligand Sets
Optopharmacology
Reagents
Toxins
按照研究领域细分：
Cancer
Cardiovascular System
Endocrinology
Immunology
Neuroscience
Pain & Inflammation
Respiratory System
