Description:PotentCB1agoNISTChemicalName:rel-5-(1,1-Dimethylheptyl)-2-[(1R,3S)-3-hydroxycyclohexyl]phenolPurity:≥98%(HPLC)BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferencesBiologicalActivityPotentCB1receptoragonist(Ki=2.2nM).Exhibitsanalgesic,motordepressant,anticonvulsantandhypothermiceffectsinvivo.TechnicalDataM.Wt318.49FormulaC21H34O2StorageStoreat-20°CPurity≥98%(HPLC)CASNumber70434-82-1PubChemID90488849InChIKeyOWPXDWMENLSANZ-OPRWNZNUSA-NSmilesCC(CCCCCC)(C)C(C=C2O)=CC=[C@@]2[C@H]1CCC[C@@H](O)C1.CC(CCCCCC)(C)C(C=C4O)=CC=[C@@]4[C@@H]3CCC[C@H](O)C3Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.AllTocrisproductsareintendedforlaboratoryresearchuseonly.SolubilityDataSolventMaxConc.mg/mLMaxConc.mMSolubilityDMSO31.85100ethanol31.85100PreparingStockSolutionsThefollowingdataisbasedontheproductmolecularweight318.49.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.Concentration/SolventVolume/Mass1mg5mg10mg1mM3.14mL15.7mL31.4mL5mM0.63mL3.14mL6.28mL10mM0.31mL1.57mL3.14mL50mM0.06mL0.31mL0.63mLMolarityCalculatorMolarityCalculatorCalculatethemass,volume,orconcentrationrequiredforasolution.ReconstitutionCalculatorReconstitutionCalculatorDilutionCalculatorDilutionCalculatorCalculatethedilutionrequiredtoprepareastocksolution.ProductDatasheetsCertificateofAnalysis/ProductDatasheetSafetyDatasheetSelectanotherlanguage:EnglishGermanFrenchSpanishViewSDSReferencesReferencesarepublicationsthatsupporttheproducts'biologicalactivity.Weissmanetal(1982)CannABImimeticactivityfromCP-47,497,aderivativeof3-phenylcyclohexanol.J.Pharmacol.Exp.Ther.223516PMID:6290642Melvinetal(1993)Structure-activityrelationshipsforcannabinoidreceptor-bindingandanalgesicactivity:studiesofbicycliccannabinoidanalogs.Mol.Pharmacol.441008PMID:8246904Huffmanetal(2008)Synthesisandpharmacologyof1-deoxyanalogsofCP-47,497andCP-55,940.Bioorg.Med.Chem.16322PMID:17919913Keywords:(±)-CP47497,supplier,Potent,CB1,agonists,cannabinoids,Receptors,(±)-CP47497,cb1r,CB1,Receptors,CB1,Receptors,TocrisBioscience
Tocris Bioscience是一家专卖生命科学研究chemicals, peptides and antibodies的知名品牌,其产品也广为各大药厂、大学、研究机构,超过五万名科学研究者所采用。 目前,產品內容已超過一千六百種以上,並每年持續不斷的增加新的產品。目前,产品内容已超过一千六百种以上,并每年持续不断的增加新的产品。
Tocris bioscience是位于英国布里斯托尔(Bristol)的高品质试剂提供商,共有2000多种产品,主要集中在神经科学和信号传导领域,产品类型包括小分子、多肽、抗体、配体和化合物筛选文库等,主要产品包括GPCR ligands,神经传递素,离子通道调控剂,信号通路抑制剂等,这些产品被广泛选择性地用于阻断或激活生物学通路。Tocris是世界上神经科学研究领域无可争议的领导者,其生产的影响神经系统的化学物质被多次引用,这些物质很多都来自Jeff Watkins(Tocris 的创立人)在Bristol大学原创性的研究工作。
Tocris Bioscience的主要产品包括:
Small Molecules
Peptides
Aptamers
Controlled Substances
Compound Libraries
DREADD Ligands
Fluorescent Imaging
Ligand Sets
Optopharmacology
Reagents
Toxins
按照研究领域细分:
Cancer
Cardiovascular System
Endocrinology
Immunology
Neuroscience
Pain & Inflammation
Respiratory System