Description:EndogenousCB1agoNISTAlternativeNames:DocosatetraenylethanolamideChemicalName:N-(2-Hydroxyethyl)-7Z,10Z,13Z,16Z-docosatetraenamideBIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferencesBiologicalActivityPotentendocannABInoidandanandamide(Cat.No.1339)analogthatactivatesCB1receptorsinmicrogliaandbindstoratsynaptosomalmembranes(Ki=34.4nM).Cannabimimeticinvivo.TechnicalDataM.Wt375.59FormulaC24H41NO2StorageDesiccateat-20°CCASNumber150314-35-5PubChemID5282273InChIKeyFMVHVRYFQIXOAF-DOFZRALJSA-NSmilesCCCCCC=C/CC=C/C/C=CC/C=CCCCCCC(NCCO)=OThetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.AllTocrisproductsareintendedforlaboratoryresearchuseonly.SolubilityDataSolubilitySolubleinethanol(suppliedpre-dissolvedinanhydrousethanol,5mg/ml)PreparingStockSolutionsThefollowingdataisbasedontheproductmolecularweight375.59.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.Concentration/SolventVolume/Mass1mg5mg10mg1mM2.66mL13.31mL26.62mL5mM0.53mL2.66mL5.32mL10mM0.27mL1.33mL2.66mL50mM0.05mL0.27mL0.53mLMolarityCalculatorMolarityCalculatorCalculatethemass,volume,orconcentrationrequiredforasolution.ReconstitutionCalculatorReconstitutionCalculatorDilutionCalculatorDilutionCalculatorCalculatethedilutionrequiredtoprepareastocksolution.ProductDatasheetsCertificateofAnalysis/ProductDatasheetSafetyDatasheetSelectanotherlanguage:EnglishGermanFrenchSpanishViewSDSReferencesReferencesarepublicationsthatsupporttheproducts'biologicalactivity.Bargetal(1995)Cannabinomimeticbehavioraleffectsofandadenylatecyclaseinhibitionbytwonewendogenousanandamides.Eur.J.Pharmacol.287145PMID:8749028Hanusetal(1993)Twonewunsaturatedfattyacidethanolamidesinbrainthatbindtothecannabinoidreceptor.J.Med.Chem.363032PMID:8411021Walteretal(2001)Microglialcellsproduceendocannabinoidsandexpressfunctionalcannabinoidreceptors:evidencethatdocosatetraenylethanolamide(DEA)isanadditionalendocannabinoid.Soc.Neurosci.Abstr.634.16PMID:Keywords:DEA,supplier,Endogenous,CB1,agonists,Cannabinoids,Receptors,cb1r,Docosatetraenylethanolamide,CB1,Receptors,CB1,Receptors,TocrisBioscience
Tocris Bioscience是一家专卖生命科学研究chemicals, peptides and antibodies的知名品牌，其产品也广为各大药厂、大学、研究机构，超过五万名科学研究者所采用。 目前，產品內容已超過一千六百種以上，並每年持續不斷的增加新的產品。目前，产品内容已超过一千六百种以上，并每年持续不断的增加新的产品。
Tocris bioscience是位于英国布里斯托尔（Bristol）的高品质试剂提供商，共有2000多种产品，主要集中在神经科学和信号传导领域，产品类型包括小分子、多肽、抗体、配体和化合物筛选文库等，主要产品包括GPCR ligands，神经传递素，离子通道调控剂，信号通路抑制剂等，这些产品被广泛选择性地用于阻断或激活生物学通路。Tocris是世界上神经科学研究领域无可争议的领导者，其生产的影响神经系统的化学物质被多次引用，这些物质很多都来自Jeff Watkins（Tocris 的创立人）在Bristol大学原创性的研究工作。
Tocris Bioscience的主要产品包括：
Small Molecules
Peptides
Aptamers
Controlled Substances
Compound Libraries
DREADD Ligands
Fluorescent Imaging
Ligand Sets
Optopharmacology
Reagents
Toxins
按照研究领域细分：
Cancer
Cardiovascular System
Endocrinology
Immunology
Neuroscience
Pain & Inflammation
Respiratory System
