Description:Selective5-HT2agoNISTAlternativeNames:2,5-Dimethoxy-4-bromoamphetaminehydrochlorideChemicalName:4-Bromo-2,5-dimethoxy-α-methylbenzeneethanaminehydrochloridePurity:≥99%(HPLC)BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferencesBiologicalActivitySelective5-HT2receptoragonist(Kivaluesare0.44,59,69,831and3700nMfor5-HT2H,5-HT2L,5-HT2C,5-HT1Band5-HT1Areceptorsrespectively).Hallucinogenic.TechnicalDataM.Wt310.62FormulaC11H16BrNO2.HClStorageStoreatRTPurity≥99%(HPLC)CASNumber29705-96-2PubChemID12626562InChIKeySPBBKPOIDQIWDZ-UHFFFAOYSA-NSmilesBrC1=C(OC)C=C(CC(C)N)C(OC)=C1.ClThetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.AllTocrisproductsareintendedforlaboratoryresearchuseonly.SolubilityDataSolventMaxConc.mg/mLMaxConc.mMSolubilitywater31.06100PreparingStockSolutionsThefollowingdataisbasedontheproductmolecularweight310.62.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.Concentration/SolventVolume/Mass1mg5mg10mg1mM3.22mL16.1mL32.19mL5mM0.64mL3.22mL6.44mL10mM0.32mL1.61mL3.22mL50mM0.06mL0.32mL0.64mLMolarityCalculatorMolarityCalculatorCalculatethemass,volume,orconcentrationrequiredforasolution.ReconstitutionCalculatorReconstitutionCalculatorDilutionCalculatorDilutionCalculatorCalculatethedilutionrequiredtoprepareastocksolution.ProductDatasheetsCertificateofAnalysis/ProductDatasheetSafetyDatasheetSelectanotherlanguage:EnglishGermanFrenchSpanishViewSDSReferencesReferencesarepublicationsthatsupporttheproducts'biologicalactivity.Titileretal(1987)SelectivityofSEROtonergicdrugsformultiplebrainserotoninreceptors.Biochem.Pharmacol.363265PMID:3663239Arvanovetal(1999)Apre-andpostsynapticmodulatoryactionof5-HTandthe5-HT2A,2CreceptoragonistDOBonNMDA-evokedresponsesintheratmedialprefrontalcortex.Eur.J.Neurosci.112917PMID:10457188McKennaetal(1989)Differentiationof5-hydroxytryptamine2receptorsubtypesusing125I-R-(-)2,5-dimethoxy-4-iodo-phenylisopropylamineand3H-ketanserin.J.Neurosci.103482PMID:Keywords:DOBhydrochloride,supplier,Selective,5-HT2,agonists,Non-Selective,Serotonin,Receptors,2,5-Dimethoxy-4-bromoamphetamine,hydrochloride,Non-selective,5-HT2,Non-selective,5-HT2,TocrisBioscience
Tocris Bioscience是一家专卖生命科学研究chemicals, peptides and antibodies的知名品牌,其产品也广为各大药厂、大学、研究机构,超过五万名科学研究者所采用。 目前,產品內容已超過一千六百種以上,並每年持續不斷的增加新的產品。目前,产品内容已超过一千六百种以上,并每年持续不断的增加新的产品。
Tocris bioscience是位于英国布里斯托尔(Bristol)的高品质试剂提供商,共有2000多种产品,主要集中在神经科学和信号传导领域,产品类型包括小分子、多肽、抗体、配体和化合物筛选文库等,主要产品包括GPCR ligands,神经传递素,离子通道调控剂,信号通路抑制剂等,这些产品被广泛选择性地用于阻断或激活生物学通路。Tocris是世界上神经科学研究领域无可争议的领导者,其生产的影响神经系统的化学物质被多次引用,这些物质很多都来自Jeff Watkins(Tocris 的创立人)在Bristol大学原创性的研究工作。
Tocris Bioscience的主要产品包括:
Small Molecules
Peptides
Aptamers
Controlled Substances
Compound Libraries
DREADD Ligands
Fluorescent Imaging
Ligand Sets
Optopharmacology
Reagents
Toxins
按照研究领域细分:
Cancer
Cardiovascular System
Endocrinology
Immunology
Neuroscience
Pain & Inflammation
Respiratory System