Description:HighlypotentcannABInoidreceptoragoNISTChemicalName:(6aR)-trans-3-(1,1-Dimethylheptyl)-6a,7,10,10a-tetrahydro-1-hydroxy-6,6-dimethyl-6H-dibenzo[b,d]pyran-9-methanolPurity:≥98%(HPLC)BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferencesBiologicalActivityAhighlypotentcannabinoidreceptoragonist(Kivaluesare0.061and0.52nMatclonedhumanCB1andCB2receptorsrespectively).Inducesspatialmemorydeficitsandsuppresseshippocampalfiringratesinrats.AlsodisplaysagonistactivityatGPR55(EC50=26nM).TechnicalDataM.Wt386.57FormulaC25H38O3StorageStoreat-20°CPurity≥98%(HPLC)CASNumber112830-95-2PubChemID9821569InChIKeySSQJFGMEZBFMNV-WOJBJXKFSA-NSmilesCCCCCCC(C)(C)C1=CC(O)=C([C@@]2([H])[C@@](C(C)(C)O3)([H])CC=C(CO)C2)C3=C1Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.AllTocrisproductsareintendedforlaboratoryresearchuseonly.SolubilityDataSolventMaxConc.mg/mLMaxConc.mMSolubilityDMSO38.66100ethanol38.66100PreparingStockSolutionsThefollowingdataisbasedontheproductmolecularweight386.57.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.Concentration/SolventVolume/Mass1mg5mg10mg1mM2.59mL12.93mL25.87mL5mM0.52mL2.59mL5.17mL10mM0.26mL1.29mL2.59mL50mM0.05mL0.26mL0.52mLMolarityCalculatorMolarityCalculatorCalculatethemass,volume,orconcentrationrequiredforasolution.ReconstitutionCalculatorReconstitutionCalculatorDilutionCalculatorDilutionCalculatorCalculatethedilutionrequiredtoprepareastocksolution.ProductDatasheetsCertificateofAnalysis/ProductDatasheetSafetyDatasheetSelectanotherlanguage:EnglishGermanFrenchSpanishViewSDSReferencesReferencesarepublicationsthatsupporttheproducts'biologicalactivity.Howlettetal(1990)Stereochemicaleffectsof11-OH-Δ8-tetrahydrocannabinol-dimethylheptyltoinhibitadenylatecyclaseandbindtothecannabinoidreceptor.Neuropharmacology29161PMID:2158635Mechoulametal(1988)Enantiomericcannabinoids:stereospecificityofpsychotropicactivity.Experientia44762PMID:3416993Robinsonetal(2007)ThesyntheticcannabinoidHU210reducesspatialmemorydeficitsandsuppresseshippocampalfiringratesinrats.Br.J.Pharmacol.151688PMID:17502849Rybergetal(2007)TheorphanreceptorGPR55isanovelcannabinoidreceptor.Br.J.Pharmacol.1521092PMID:17876302Keywords:HU210,supplier,potent,cannabinoids,agonists,Non-Selective,Receptors,HU210,cb2r,cb1r,Non-selective,Cannabinoids,Non-selective,Cannabinoids,TocrisBioscience
Tocris Bioscience是一家专卖生命科学研究chemicals, peptides and antibodies的知名品牌,其产品也广为各大药厂、大学、研究机构,超过五万名科学研究者所采用。 目前,產品內容已超過一千六百種以上,並每年持續不斷的增加新的產品。目前,产品内容已超过一千六百种以上,并每年持续不断的增加新的产品。
Tocris bioscience是位于英国布里斯托尔(Bristol)的高品质试剂提供商,共有2000多种产品,主要集中在神经科学和信号传导领域,产品类型包括小分子、多肽、抗体、配体和化合物筛选文库等,主要产品包括GPCR ligands,神经传递素,离子通道调控剂,信号通路抑制剂等,这些产品被广泛选择性地用于阻断或激活生物学通路。Tocris是世界上神经科学研究领域无可争议的领导者,其生产的影响神经系统的化学物质被多次引用,这些物质很多都来自Jeff Watkins(Tocris 的创立人)在Bristol大学原创性的研究工作。
Tocris Bioscience的主要产品包括:
Small Molecules
Peptides
Aptamers
Controlled Substances
Compound Libraries
DREADD Ligands
Fluorescent Imaging
Ligand Sets
Optopharmacology
Reagents
Toxins
按照研究领域细分:
Cancer
Cardiovascular System
Endocrinology
Immunology
Neuroscience
Pain & Inflammation
Respiratory System