Description:SelectiveCB2agoNISTChemicalName:(2-Methyl-1-propyl-1H-indol-3-yl)-1-naphthalenylmethanonePurity:≥99%(HPLC)BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferencesBiologicalActivitySelectiveCB2agonist(Kivaluesare13.8and383nMasmeasuredathumanclonedCB2andCB1receptorsexpressedinCHOcells).TechnicalDataM.Wt327.43FormulaC23H21NOStorageDesiccateat-20°CPurity≥99%(HPLC)CASNumber155471-08-2PubChemID4273754InChIKeyLJSBBBWQTLXQEN-UHFFFAOYSA-NSmilesCCCN1C(C)=C(C(=O)C2=CC=CC3=CC=CC=C23)C2=CC=CC=C12Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.AllTocrisproductsareintendedforlaboratoryresearchuseonly.SolubilityDataSolubilitySolubleto10mMinDMSOandto25mMinethanolPreparingStockSolutionsThefollowingdataisbasedontheproductmolecularweight327.43.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.Concentration/SolventVolume/Mass1mg5mg10mg1mM3.05mL15.27mL30.54mL5mM0.61mL3.05mL6.11mL10mM0.31mL1.53mL3.05mL50mM0.06mL0.31mL0.61mLMolarityCalculatorMolarityCalculatorCalculatethemass,volume,orconcentrationrequiredforasolution.ReconstitutionCalculatorReconstitutionCalculatorDilutionCalculatorDilutionCalculatorCalculatethedilutionrequiredtoprepareastocksolution.ProductDatasheetsCertificateofAnalysis/ProductDatasheetSafetyDatasheetSelectanotherlanguage:EnglishGermanFrenchSpanishViewSDSReferencesReferencesarepublicationsthatsupporttheproducts'biologicalactivity.Chinetal(1999)ThethirdtransmembranehelixofthecannABInoidreceptorplaysaroleintheselectivityofaminoalkylindolesforCB2,peripheralcannabinoidreceptor.J.Pharmacol.Exp.Ther.291837PMID:10525107Griffinetal(1997)EvidenceforthepresenceofCB2-likereceptoronperipheralnerveterminals.Eur.J.Pharmacol.33953PMID:9450616Pertweeetal(1999)Pharmacologyofcannabinoidreceptorligands.Curr.Med.Chem.6635PMID:10469884Keywords:JWH015,supplier,Selective,CB2,agonists,Cannabinoids,Receptors,JWH015,cb2r,CB2,Receptors,CB2,Receptors,TocrisBioscience
Tocris Bioscience是一家专卖生命科学研究chemicals, peptides and antibodies的知名品牌,其产品也广为各大药厂、大学、研究机构,超过五万名科学研究者所采用。 目前,產品內容已超過一千六百種以上,並每年持續不斷的增加新的產品。目前,产品内容已超过一千六百种以上,并每年持续不断的增加新的产品。
Tocris bioscience是位于英国布里斯托尔(Bristol)的高品质试剂提供商,共有2000多种产品,主要集中在神经科学和信号传导领域,产品类型包括小分子、多肽、抗体、配体和化合物筛选文库等,主要产品包括GPCR ligands,神经传递素,离子通道调控剂,信号通路抑制剂等,这些产品被广泛选择性地用于阻断或激活生物学通路。Tocris是世界上神经科学研究领域无可争议的领导者,其生产的影响神经系统的化学物质被多次引用,这些物质很多都来自Jeff Watkins(Tocris 的创立人)在Bristol大学原创性的研究工作。
Tocris Bioscience的主要产品包括:
Small Molecules
Peptides
Aptamers
Controlled Substances
Compound Libraries
DREADD Ligands
Fluorescent Imaging
Ligand Sets
Optopharmacology
Reagents
Toxins
按照研究领域细分:
Cancer
Cardiovascular System
Endocrinology
Immunology
Neuroscience
Pain & Inflammation
Respiratory System