Description: Selective CB2 agonist
Chemical Name: (2-Methyl-1-propyl-1H-indol-3-yl)-1-naphthalenylmethanone
Purity: ≥99% (HPLC)
Biological Activity
Technical Data
Solubility
Calculators
Datasheets
References
Biological Activity
Selective CB2 agonist (Ki values are 13.8 and 383 nM as measured at human cloned CB2 and CB1 receptors expressed in CHO cells).
Technical Data
M. Wt
327.43
Formula
C23H21NO
Storage
Desiccate at -20°C
Purity
≥99% (HPLC)
CAS Number
155471-08-2
PubChem ID
4273754
InChI Key
LJSBBBWQTLXQEN-UHFFFAOYSA-N
Smiles
CCCN1C(C)=C(C(=O)C2=CC=CC3=CC=CC=C23)C2=CC=CC=C12
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Solubility Data
SolubilitySoluble to 10 mM in DMSO and to 25 mM in ethanol
Preparing Stock Solutions
The following data is based on the product molecular weight 327.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass
1 mg
5 mg
10 mg
1 mM
3.05 mL
15.27 mL
30.54 mL
5 mM
0.61 mL
3.05 mL
6.11 mL
10 mM
0.31 mL
1.53 mL
3.05 mL
50 mM
0.06 mL
0.31 mL
0.61 mL
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Product Datasheets
Certificate of Analysis / Product Datasheet
Safety Datasheet
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References
References are publications that support the products' biological activity.
Chin
et al (1999) The third transmembrane helix of the cannabinoid receptor plays a role in the selectivity of aminoalkylindoles for CB2, peripheral cannabinoid receptor. J.Pharmacol.Exp.Ther. 291 837 PMID: 10525107
Griffin
et al (1997) Evidence for the presence of CB2-like receptor on peripheral nerve terminals. Eur.J.Pharmacol. 339 53 PMID: 9450616
Pertwee
et al (1999) Pharmacology of cannabinoid receptor ligands. Curr.Med.Chem. 6 635 PMID: 10469884
Keywords: JWH 015, supplier, Selective, CB2, agonists, Cannabinoids, Receptors, JWH015, cb2r, CB2, Receptors, CB2, Receptors, Tocris Bioscience
Tocris Bioscience是一家专卖生命科学研究chemicals, peptides and antibodies的知名品牌，其产品也广为各大药厂、大学、研究机构，超过五万名科学研究者所采用。 目前，產品內容已超過一千六百種以上，並每年持續不斷的增加新的產品。目前，产品内容已超过一千六百种以上，并每年持续不断的增加新的产品。
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