Description:Inhibitorof5-HTanddopamineuptake;hallucinogenicAlternativeNames:MethylenedioxymethamphetaminehydrochlorideChemicalName:N,α,-Dimethyl-3,4-methylenedioxyphenethylaminehydrochloridePurity:≥98%(HPLC)BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferencesBiologicalActivityHallucinogeniccompoundthatinhibits5-HTanddopamineuptake.TechnicalDataM.Wt229.7FormulaC11H15NO2.HClStorageStoreatRTPurity≥98%(HPLC)CASNumber92279-84-0PubChemID71285InChIKeyLUWHVONVCYWRMZ-UHFFFAOYSA-NSmilesCC(NC)CC1=CC(OCO2)=C2C=C1.ClThetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.AllTocrisproductsareintendedforlaboratoryresearchuseonly.SolubilityDataSolventMaxConc.mg/mLMaxConc.mMSolubilitywater22.97100PreparingStockSolutionsThefollowingdataisbasedontheproductmolecularweight229.7.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.Concentration/SolventVolume/Mass1mg5mg10mg1mM4.35mL21.77mL43.54mL5mM0.87mL4.35mL8.71mL10mM0.44mL2.18mL4.35mL50mM0.09mL0.44mL0.87mLMolarityCalculatorMolarityCalculatorCalculatethemass,volume,orconcentrationrequiredforasolution.ReconstitutionCalculatorReconstitutionCalculatorDilutionCalculatorDilutionCalculatorCalculatethedilutionrequiredtoprepareastocksolution.ProductDatasheetsCertificateofAnalysis/ProductDatasheetSafetyDatasheetSelectanotherlanguage:EnglishGermanFrenchSpanishViewSDSReferencesReferencesarepublicationsthatsupporttheproducts'biologicalactivity.Iravanietal(2000)Directeffectsof3,4-methylenedioxymethamphetamine(MDMA)onSEROtoninordopaminereleaseanduptakeinthecaudateputamen,nucleusaccumbens,substantianigraparsreticulata,andthedorsalraphenucleusslices.Synapse36275PMID:10819905Fleckensteinetal(2007)Newinsightsintothemechanismofactionofamphetamines.Annu.Rev.Pharmacol.Toxicol.47681PMID:17209801Boyleetal(2007)MDMA("eCSTasy")suppressestheinnateIFN-γresponseinvivo:acriticalrolefortheanti-inflammatorycytokineIL-10.Eur.J.Pharmacol.572228PMID:17689526Keywords:(±)-MDMAhydrochloride,supplier,inhibitors,inhibits,5-HT,dopamine,reuptake,hallucinogenic,Serotonin,Transporters,SERT,5-Hydroxytryptamine,Monoamine,Neurotransmitter,DAT,Methylenedioxymethamphetamine,hydrochloride,(±)-Methylenedioxymethamphetamine,hydrochloride,5-HT,Transporters,Dopamine,Transporters,5-HT,Transporters,TocrisBioscience
Tocris Bioscience是一家专卖生命科学研究chemicals, peptides and antibodies的知名品牌，其产品也广为各大药厂、大学、研究机构，超过五万名科学研究者所采用。 目前，產品內容已超過一千六百種以上，並每年持續不斷的增加新的產品。目前，产品内容已超过一千六百种以上，并每年持续不断的增加新的产品。
Tocris bioscience是位于英国布里斯托尔（Bristol）的高品质试剂提供商，共有2000多种产品，主要集中在神经科学和信号传导领域，产品类型包括小分子、多肽、抗体、配体和化合物筛选文库等，主要产品包括GPCR ligands，神经传递素，离子通道调控剂，信号通路抑制剂等，这些产品被广泛选择性地用于阻断或激活生物学通路。Tocris是世界上神经科学研究领域无可争议的领导者，其生产的影响神经系统的化学物质被多次引用，这些物质很多都来自Jeff Watkins（Tocris 的创立人）在Bristol大学原创性的研究工作。
Tocris Bioscience的主要产品包括：
Small Molecules
Peptides
Aptamers
Controlled Substances
Compound Libraries
DREADD Ligands
Fluorescent Imaging
Ligand Sets
Optopharmacology
Reagents
Toxins
按照研究领域细分：
Cancer
Cardiovascular System
Endocrinology
Immunology
Neuroscience
Pain & Inflammation
Respiratory System
