Description:BenzodiazepineagoNISTAlternativeNames:Dormicum,Ro21-3981/001ChemicalName:8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepinehydrochloridePurity:≥99%(HPLC)BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferencesBiologicalActivitySedative/hypnoticagentthatactsattheGABAAreceptorbenzodiazepinemodulatorysite.TechnicalDataM.Wt362.23FormulaC18H13ClFN3.HClStorageDesiccateatRTPurity≥99%(HPLC)CASNumber59467-96-8PubChemID43032InChIKeyPLYSCVSCYOQVRP-UHFFFAOYSA-NSmilesFC(C=CC=C4)=C4C3=NCC1=CN=C(C)N1C2=CC=C(Cl)C=C23.ClThetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.AllTocrisproductsareintendedforlaboratoryresearchuseonly.SolubilityDataSolventMaxConc.mg/mLMaxConc.mMSolubilitywater9.0625PreparingStockSolutionsThefollowingdataisbasedontheproductmolecularweight362.23.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.Concentration/SolventVolume/Mass1mg5mg10mg1mM2.76mL13.8mL27.61mL5mM0.55mL2.76mL5.52mL10mM0.28mL1.38mL2.76mL50mM0.06mL0.28mL0.55mLMolarityCalculatorMolarityCalculatorCalculatethemass,volume,orconcentrationrequiredforasolution.ReconstitutionCalculatorReconstitutionCalculatorDilutionCalculatorDilutionCalculatorCalculatethedilutionrequiredtoprepareastocksolution.ProductDatasheetsCertificateofAnalysis/ProductDatasheetSafetyDatasheetSelectanotherlanguage:EnglishGermanFrenchSpanishViewSDSReferencesReferencesarepublicationsthatsupporttheproducts'biologicalactivity.Kanto(1985)Midazolam:thefirstwater-solublebenzodiazepine.Pharmacology,pharmacokineticsandefficacyininsomniaandanesthesia.Pharmacotherapy5138PMID:3161005OlkkolaandAhonen(2008)Midazolamandotherbenzodiazepines.Handb.Exp.Pharmacol.182335PMID:18175099Keywords:Midazolamhydrochloride,supplier,Benzodiazepine,agonists,GABAA,Receptors,Ro213981001,Dormicum,Ro,21-3981/001,GABAA,Receptors,GABAA,Receptors,TocrisBioscience
Tocris Bioscience是一家专卖生命科学研究chemicals, peptides and antibodies的知名品牌，其产品也广为各大药厂、大学、研究机构，超过五万名科学研究者所采用。 目前，產品內容已超過一千六百種以上，並每年持續不斷的增加新的產品。目前，产品内容已超过一千六百种以上，并每年持续不断的增加新的产品。
Tocris bioscience是位于英国布里斯托尔（Bristol）的高品质试剂提供商，共有2000多种产品，主要集中在神经科学和信号传导领域，产品类型包括小分子、多肽、抗体、配体和化合物筛选文库等，主要产品包括GPCR ligands，神经传递素，离子通道调控剂，信号通路抑制剂等，这些产品被广泛选择性地用于阻断或激活生物学通路。Tocris是世界上神经科学研究领域无可争议的领导者，其生产的影响神经系统的化学物质被多次引用，这些物质很多都来自Jeff Watkins（Tocris 的创立人）在Bristol大学原创性的研究工作。
Tocris Bioscience的主要产品包括：
Small Molecules
Peptides
Aptamers
Controlled Substances
Compound Libraries
DREADD Ligands
Fluorescent Imaging
Ligand Sets
Optopharmacology
Reagents
Toxins
按照研究领域细分：
Cancer
Cardiovascular System
Endocrinology
Immunology
Neuroscience
Pain & Inflammation
Respiratory System
