Description:PsychostimulantAlternativeNames:CRL40476ChemicalName:2-[(Diphenylmethyl)sulfinyl]acetamidePurity:≥98%(HPLC)BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferencesBiologicalActivityPsychostimulantthatdisplaysneuroprotectiveandantiparkinsonianactivityinaprimatemodelofParkinson'sdisease.Promotesvigilenceandwakefulnesswithoutthecentralandperipheralsideeffectsassociatedwithconventionaldopaminergicpsychostimulants.Mechanismofactionisnotfullyunderstood,possIBLyviamodulationofcatecholamine/GABAergicneurotransmission.TechnicalDataM.Wt273.35FormulaC15H15NO2SStorageStoreat+4°CPurity≥98%(HPLC)CASNumber68693-11-8PubChemID4236InChIKeyYFGHCGITMMYXAQ-UHFFFAOYSA-NSmilesO=S(CC(N)=O)C(C2=CC=CC=C2)C1=CC=CC=C1Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.AllTocrisproductsareintendedforlaboratoryresearchuseonly.SolubilityDataSolventMaxConc.mg/mLMaxConc.mMSolubilityDMSO20.575ethanol2.7310PreparingStockSolutionsThefollowingdataisbasedontheproductmolecularweight273.35.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.Concentration/SolventVolume/Mass1mg5mg10mg1mM3.66mL18.29mL36.58mL5mM0.73mL3.66mL7.32mL10mM0.37mL1.83mL3.66mL50mM0.07mL0.37mL0.73mLMolarityCalculatorMolarityCalculatorCalculatethemass,volume,orconcentrationrequiredforasolution.ReconstitutionCalculatorReconstitutionCalculatorDilutionCalculatorDilutionCalculatorCalculatethedilutionrequiredtoprepareastocksolution.ProductDatasheetsCertificateofAnalysis/ProductDatasheetSafetyDatasheetSelectanotherlanguage:EnglishGermanFrenchSpanishViewSDSReferencesReferencesarepublicationsthatsupporttheproducts'biologicalactivity.Ferraroetal(1997)Modafinil:anantinarcolepticdrugwithadifferentneuRochemicalprofiletod-amphetamineanddopamineuptakeblockers.Biol.Psychiatry421181PMID:9426889Jenneretal(2000)Antiparkinsonianandneuroprotectiveeffectsofmodafinilinthemtpt-treatedcommonmarmoset.Exp.BrainRes.133178PMID:10968218Madrasetal(2006)Modafiniloccupiesdopamineandnorepinephrinetransportersinvivoandmodulatesthetransportersandtraceamineactivityinvitro.J.Pharmacol.Exp.Ther.319561PMID:16885432Keywords:Modafinil,supplier,Psychostimulant,Adrenergic,Compounds,Adrenoceptors,Receptors,Dopaminergic,Dopamine,GABA,CRL40476,CRL,40476,Adrenergic,Related,Compounds,Dopaminergic-Related,Miscellaneous,GABA,GABAB,Receptors,Adrenergic,Related,Compounds,TocrisBioscience
Tocris Bioscience是一家专卖生命科学研究chemicals, peptides and antibodies的知名品牌，其产品也广为各大药厂、大学、研究机构，超过五万名科学研究者所采用。 目前，產品內容已超過一千六百種以上，並每年持續不斷的增加新的產品。目前，产品内容已超过一千六百种以上，并每年持续不断的增加新的产品。
Tocris bioscience是位于英国布里斯托尔（Bristol）的高品质试剂提供商，共有2000多种产品，主要集中在神经科学和信号传导领域，产品类型包括小分子、多肽、抗体、配体和化合物筛选文库等，主要产品包括GPCR ligands，神经传递素，离子通道调控剂，信号通路抑制剂等，这些产品被广泛选择性地用于阻断或激活生物学通路。Tocris是世界上神经科学研究领域无可争议的领导者，其生产的影响神经系统的化学物质被多次引用，这些物质很多都来自Jeff Watkins（Tocris 的创立人）在Bristol大学原创性的研究工作。
Tocris Bioscience的主要产品包括：
Small Molecules
Peptides
Aptamers
Controlled Substances
Compound Libraries
DREADD Ligands
Fluorescent Imaging
Ligand Sets
Optopharmacology
Reagents
Toxins
按照研究领域细分：
Cancer
Cardiovascular System
Endocrinology
Immunology
Neuroscience
Pain & Inflammation
Respiratory System
