Description:Highaffinity,water-solubleCB1/CB2agoNISTChemicalName:(6aR,10aR)-6a,7,10,10a-Tetrahydro-3-[5-(1H-imidazol-1-yl)-1,1-dimethylpentyl]-6,6,9-trimethyl-6H-dibenzo[b,d]pyran-1-olhydrochloridePurity:≥99%(HPLC)BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferencesBiologicalActivityHighaffinity,water-solubleCB1/CB2receptoragonist(Kivaluesare1.5and0.32nMforCB1andCB2receptorsrespectively).Activeinvivofollowingi.v.andi.c.v.administration.LicensingInformationSoldunderlicensefromVCU-IPFTechnicalDataM.Wt445.04FormulaC26H36N2O2.HClStorageStoreat-20°CPurity≥99%(HPLC)CASNumber874745-43-4PubChemID24848973InChIKeyLSHUCXYFAOTXLT-MUCZFFFMSA-NSmilesOC1=CC(C(C)(C)CCCCN4C=CN=C4)=CC3=[C@@]1[C@H]2[C@H]([C@@](C)(C)O3)CC=C(C)C2.ClThetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.AllTocrisproductsareintendedforlaboratoryresearchuseonly.SolubilityDataSolventMaxConc.mg/mLMaxConc.mMSolubilityethanol44.5100water8.920mMwithgentlewarmingPreparingStockSolutionsThefollowingdataisbasedontheproductmolecularweight445.04.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.Concentration/SolventVolume/Mass1mg5mg10mg1mM2.25mL11.23mL22.47mL5mM0.45mL2.25mL4.49mL10mM0.22mL1.12mL2.25mL50mM0.04mL0.22mL0.45mLMolarityCalculatorMolarityCalculatorCalculatethemass,volume,orconcentrationrequiredforasolution.ReconstitutionCalculatorReconstitutionCalculatorDilutionCalculatorDilutionCalculatorCalculatethedilutionrequiredtoprepareastocksolution.ProductDatasheetsCertificateofAnalysis/ProductDatasheetSafetyDatasheetSelectanotherlanguage:EnglishGermanFrenchSpanishViewSDSReferencesReferencesarepublicationsthatsupporttheproducts'biologicalactivity.Martinetal(2006)Pharmacologicalcharacterizationofnovelwater-solublecannABInoids.J.Pharmacol.Exp.Ther.3181230PMID:16757541Keywords:O-2545hydrochloride,supplier,High,affinity,water-soluble,CB1/CB2,agonists,Non-Selective,cannabinoids,Receptors,cb2r,cb1r,Non-selective,Cannabinoids,Non-selective,Cannabinoids,TocrisBioscience
Tocris Bioscience是一家专卖生命科学研究chemicals, peptides and antibodies的知名品牌，其产品也广为各大药厂、大学、研究机构，超过五万名科学研究者所采用。 目前，產品內容已超過一千六百種以上，並每年持續不斷的增加新的產品。目前，产品内容已超过一千六百种以上，并每年持续不断的增加新的产品。
Tocris bioscience是位于英国布里斯托尔（Bristol）的高品质试剂提供商，共有2000多种产品，主要集中在神经科学和信号传导领域，产品类型包括小分子、多肽、抗体、配体和化合物筛选文库等，主要产品包括GPCR ligands，神经传递素，离子通道调控剂，信号通路抑制剂等，这些产品被广泛选择性地用于阻断或激活生物学通路。Tocris是世界上神经科学研究领域无可争议的领导者，其生产的影响神经系统的化学物质被多次引用，这些物质很多都来自Jeff Watkins（Tocris 的创立人）在Bristol大学原创性的研究工作。
Tocris Bioscience的主要产品包括：
Small Molecules
Peptides
Aptamers
Controlled Substances
Compound Libraries
DREADD Ligands
Fluorescent Imaging
Ligand Sets
Optopharmacology
Reagents
Toxins
按照研究领域细分：
Cancer
Cardiovascular System
Endocrinology
Immunology
Neuroscience
Pain & Inflammation
Respiratory System
