Description:Non-competitiveNMDAreceptorantagoNISTAlternativeNames:PCPChemicalName:1-(1-Phenylcyclohexyl)piperidinehydrochloridePurity:≥99%(HPLC)BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferencesBiologicalActivityNon-competitiveNMDAreceptorantagonistandsigmareceptoragonist.Psychostimulant;inducesrotationalbehavior,head-weavingandcognitivedysfunctioninrats.TechnicalDataM.Wt279.85FormulaC17H25N.HClStorageStoreatRTPurity≥99%(HPLC)CASNumber956-90-1PubChemID13727InChIKeyBUAJNGPDPGKBGV-UHFFFAOYSA-NSmilesN2(CCCCC2)C1(C3=CC=CC=C3)CCCCC1.ClThetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.AllTocrisproductsareintendedforlaboratoryresearchuseonly.SolubilityDataSolventMaxConc.mg/mLMaxConc.mMSolubilitywater11.1940PreparingStockSolutionsThefollowingdataisbasedontheproductmolecularweight279.85.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.Concentration/SolventVolume/Mass1mg5mg10mg1mM3.57mL17.87mL35.73mL5mM0.71mL3.57mL7.15mL10mM0.36mL1.79mL3.57mL50mM0.07mL0.36mL0.71mLMolarityCalculatorMolarityCalculatorCalculatethemass,volume,orconcentrationrequiredforasolution.ReconstitutionCalculatorReconstitutionCalculatorDilutionCalculatorDilutionCalculatorCalculatethedilutionrequiredtoprepareastocksolution.ProductDatasheetsCertificateofAnalysis/ProductDatasheetSafetyDatasheetSelectanotherlanguage:EnglishGermanFrenchSpanishViewSDSReferencesReferencesarepublicationsthatsupporttheproducts'biologicalactivity.Lindersetal(1993)SynthesisandbindingpropertiesofMK-801isothiocyanates;(+)-3-isothiocyanato-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-iminehydrochloride:anewpotentandselectiveelectrophilicaffinityligandfortheNMDAreceptor-cJ.Med.Chem.362499PMID:8355251Jinetal(1997)Theinvolvementofσreceptorsinthechoicereactionperformancedeficitsinducedbyphencyclidine.Eur.J.Pharmacol.319147PMID:9042584Sharp(1997)Phencyclidine(PCP)actsatσsitestoinducec-fosgeneexpression.BrainRes.75851PMID:9203533Keywords:Phencyclidinehydrochloride,supplier,σ,sigma,receptor,agonists,Non-competitive,NMDA,antagonists,General,Receptors,Glutamate,N-Methyl-D-Aspartate,iGluR,Ionotropic,PCP,NMDA,Receptors,Sigma-Related,NMDA,Receptors,TocrisBioscience
Tocris Bioscience是一家专卖生命科学研究chemicals, peptides and antibodies的知名品牌，其产品也广为各大药厂、大学、研究机构，超过五万名科学研究者所采用。 目前，產品內容已超過一千六百種以上，並每年持續不斷的增加新的產品。目前，产品内容已超过一千六百种以上，并每年持续不断的增加新的产品。
Tocris bioscience是位于英国布里斯托尔（Bristol）的高品质试剂提供商，共有2000多种产品，主要集中在神经科学和信号传导领域，产品类型包括小分子、多肽、抗体、配体和化合物筛选文库等，主要产品包括GPCR ligands，神经传递素，离子通道调控剂，信号通路抑制剂等，这些产品被广泛选择性地用于阻断或激活生物学通路。Tocris是世界上神经科学研究领域无可争议的领导者，其生产的影响神经系统的化学物质被多次引用，这些物质很多都来自Jeff Watkins（Tocris 的创立人）在Bristol大学原创性的研究工作。
Tocris Bioscience的主要产品包括：
Small Molecules
Peptides
Aptamers
Controlled Substances
Compound Libraries
DREADD Ligands
Fluorescent Imaging
Ligand Sets
Optopharmacology
Reagents
Toxins
按照研究领域细分：
Cancer
Cardiovascular System
Endocrinology
Immunology
Neuroscience
Pain & Inflammation
Respiratory System
