Description:TFAsaltofvirodhamine,anendogenouscannABInoidreceptormixedagoNIST/antagonistChemicalName:O-(2-Aminoethyl)-5Z,8Z,11Z,14Z-eicosatetraenoatetrifluoroacetatePurity:≥98%(HPLC)BIOLOGicalActivityTechnicalDataDatasheetsReferencesBiologicalActivityTFAsaltofvirodhamine,anendogenouscannabinoidreceptormixedagonist/antagonistthatisfoundinhigherconcentrationsperipherallythananandamide.VirodhamineisafullagonistatGPR55andCB2andpartialagonist/antagonistatCB1(EC50valuesare12,381and2920nMatGPR55,CB2andCB1receptorsrespectively).TechnicalDataM.Wt461.56FormulaC22H37NO2.CF3CO2HStorageStoreat-20°CPurity≥98%(HPLC)CASNumber1415264-56-0PubChemID91691131InChIKeyAPQWCQIPZHJFAU-XVSDJDOKSA-NSmilesO=C(OCCN)CCCC=C/CC=C/C/C=CC/C=CCCCCC.FC(F)(F)C(O)=OThetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.AllTocrisproductsareintendedforlaboratoryresearchuseonly.PreparingStockSolutionsThefollowingdataisbasedontheproductmolecularweight461.56.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.Concentration/SolventVolume/Mass1mg5mg10mg1mM2.17mL10.83mL21.67mL5mM0.43mL2.17mL4.33mL10mM0.22mL1.08mL2.17mL50mM0.04mL0.22mL0.43mLMolarityCalculatorMolarityCalculatorCalculatethemass,volume,orconcentrationrequiredforasolution.ReconstitutionCalculatorReconstitutionCalculatorDilutionCalculatorDilutionCalculatorCalculatethedilutionrequiredtoprepareastocksolution.ProductDatasheetsCertificateofAnalysis/ProductDatasheetSafetyDatasheetSelectanotherlanguage:EnglishGermanFrenchSpanishViewSDSReferencesReferencesarepublicationsthatsupporttheproducts'biologicalactivity.Porteretal(2002)Characterizationofanovelendocannabinoid,virodhamine,withantagonistactivityattheCB1receptor.J.Pharmacol.Exp.Ther.3011020PMID:12023533Keywords:Virodhaminetrifluoroacetate,supplier,Virodhamine,TFA,GPR55,CB2,agonists,CB1,partial,antagonists,non-selective,cannabinoids,receptors,cb2r,cb1r,Trifluoroacetic,acid,salt,Non-selective,Cannabinoids,Non-selective,Cannabinoids,TocrisBioscience
Tocris Bioscience是一家专卖生命科学研究chemicals, peptides and antibodies的知名品牌，其产品也广为各大药厂、大学、研究机构，超过五万名科学研究者所采用。 目前，產品內容已超過一千六百種以上，並每年持續不斷的增加新的產品。目前，产品内容已超过一千六百种以上，并每年持续不断的增加新的产品。
Tocris bioscience是位于英国布里斯托尔（Bristol）的高品质试剂提供商，共有2000多种产品，主要集中在神经科学和信号传导领域，产品类型包括小分子、多肽、抗体、配体和化合物筛选文库等，主要产品包括GPCR ligands，神经传递素，离子通道调控剂，信号通路抑制剂等，这些产品被广泛选择性地用于阻断或激活生物学通路。Tocris是世界上神经科学研究领域无可争议的领导者，其生产的影响神经系统的化学物质被多次引用，这些物质很多都来自Jeff Watkins（Tocris 的创立人）在Bristol大学原创性的研究工作。
Tocris Bioscience的主要产品包括：
Small Molecules
Peptides
Aptamers
Controlled Substances
Compound Libraries
DREADD Ligands
Fluorescent Imaging
Ligand Sets
Optopharmacology
Reagents
Toxins
按照研究领域细分：
Cancer
Cardiovascular System
Endocrinology
Immunology
Neuroscience
Pain & Inflammation
Respiratory System
