Description:Potent,selectiveD1-likeagoNISTChemicalName:cis-(±)-1-(Aminomethyl)-3,4-dihydro-3-phenyl-1H-2-benzopyran-5,6-diolhydrochloridePurity:≥98%(HPLC)BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferencesBiologicalActivityPotentandselectiveD1-likedopaminereceptoragonist(EC50valuesare2.1and3910nMforD1-likeandD2-likereceptorsrespectively).Centrallyactivefollowingsystemicadministrationinvivo.TechnicalDataM.Wt307.78FormulaC16H17NO3.HClStorageDesiccateat+4°CPurity≥98%(HPLC)CASNumber130465-39-3PubChemID9904672InChIKeyPQPGUUQPTSMLKU-YYLIZZNMSA-NSmilesOC1=C(O)C=CC2=C1C[C@@H]([C@]3=CC=CC=C3)O[C@H]2CN.ClThetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.AllTocrisproductsareintendedforlaboratoryresearchuseonly.SolubilityDataSolventMaxConc.mg/mLMaxConc.mMSolubilitywater15.3950PreparingStockSolutionsThefollowingdataisbasedontheproductmolecularweight307.78.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.Concentration/SolventVolume/Mass1mg5mg10mg1mM3.25mL16.25mL32.49mL5mM0.65mL3.25mL6.5mL10mM0.32mL1.62mL3.25mL50mM0.06mL0.32mL0.65mLMolarityCalculatorMolarityCalculatorCalculatethemass,volume,orconcentrationrequiredforasolution.ReconstitutionCalculatorReconstitutionCalculatorDilutionCalculatorDilutionCalculatorCalculatethedilutionrequiredtoprepareastocksolution.ProductDatasheetsCertificateofAnalysis/ProductDatasheetSafetyDatasheetSelectanotherlanguage:EnglishGermanFrenchSpanishViewSDSReferencesReferencesarepublicationsthatsupporttheproducts'biologicalactivity.DeveneyandWaddingto(1997)Psychopharmacologicaldistinctionbetweennovelfull-efficacy"D1-like"dopaminereceptoragonists.Pharmacol.Biochem.Behav.58551PMID:9300618KebABIanetal(1990)A68930:apotentandspecificagonistfortheD-1dopaminereceptor.Am.J.Hypertens.340SPMID:2143387Quagliaetal(1990)(1R,3S)-1-(Aminomethyl)-3,4-dihydro-5,6-dihydroxy-3-phenyl-1H-2-benzopyran:apotentandselectiveD1agonist.J.Med.Chem.332948PMID:1977907Keywords:A68930hydrochloride,supplier,Potent,selective,D1-like,agonists,Dopamine,D1,Receptors,D5,dopaminergic,A68930,hydrochloride,D1,and,D5,Receptors,D1,and,D5,Receptors,TocrisBioscience
Tocris Bioscience是一家专卖生命科学研究chemicals, peptides and antibodies的知名品牌，其产品也广为各大药厂、大学、研究机构，超过五万名科学研究者所采用。 目前，產品內容已超過一千六百種以上，並每年持續不斷的增加新的產品。目前，产品内容已超过一千六百种以上，并每年持续不断的增加新的产品。
Tocris bioscience是位于英国布里斯托尔（Bristol）的高品质试剂提供商，共有2000多种产品，主要集中在神经科学和信号传导领域，产品类型包括小分子、多肽、抗体、配体和化合物筛选文库等，主要产品包括GPCR ligands，神经传递素，离子通道调控剂，信号通路抑制剂等，这些产品被广泛选择性地用于阻断或激活生物学通路。Tocris是世界上神经科学研究领域无可争议的领导者，其生产的影响神经系统的化学物质被多次引用，这些物质很多都来自Jeff Watkins（Tocris 的创立人）在Bristol大学原创性的研究工作。
Tocris Bioscience的主要产品包括：
Small Molecules
Peptides
Aptamers
Controlled Substances
Compound Libraries
DREADD Ligands
Fluorescent Imaging
Ligand Sets
Optopharmacology
Reagents
Toxins
按照研究领域细分：
Cancer
Cardiovascular System
Endocrinology
Immunology
Neuroscience
Pain & Inflammation
Respiratory System
